What is the distance between Orlando and Panama City?

The distance between the two cities is 282 miles (454 km).

What are the departure and arrival stations when taking the bus from Orlando to Panama City?

If you're headed to Panama City from Orlando, chances are that your bus will depart from Orlando Bus Station and arrive at Panama City Greyhound Bus Station. These are the most popular departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Panama City?

Once in Panama City, you can start exploring the city and discover its surroundings. The top sights and things to do are Bird Watching, Jungle Land Panama, Inter-Oceanic Canal Muesum, Panama Rainforest Discovery Center and Casco Antiguo.

Bus Orlando to Panama City from $65 | Refundable Tickets

Next bus departures

Next departures for Orlando to Panama City on November 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	CheapestFastest
	Bus	5:40am	Orlando Bus Station	9h 20m	2:00pm	Panama City Beach Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	No tags

Next departures for Orlando to Panama City on November 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	CheapestFastest
	Bus	5:40am	Orlando Bus Station	9h 20m	2:00pm	Panama City Beach Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	No tags

Next departures for Orlando to Panama City on November 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:40am	Orlando Bus Station	9h 20m	2:00pm	Panama City Beach Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	1:50pm	Orlando Bus Station	8h 45m	9:35pm	Panama City Beach Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:05pm	The Florida Mall	9h 30m	9:35pm	Panama City Beach Station	No tags

Last refresh of the prices: Today at 12:51 AM EST.

Get from Orlando to Panama City

This route is served by bus only

The journey takes about 9 hours 20 minutes and with fares starting at just $55, it presents an excellent value for a comfortable ride.

4bus per day

9h 20mAverage Duration

286 milesDistance

12kgCO₂ emissions

Compare bus companies

Greyhound

3.5/587,370 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Orlando Panama City recent customer reviews

The journey was very pleasant, thanks to the team of experienced, helpful and caring workers. I did not like the long layover.

Sharon D.

December 24, 2023

My major issue was that I could not connect to the WiFi. My final arrangements for my pickup wasn't made. I was depending on the bus WiFi for that. As the bus was delayed, the layover at Tallahassee was shortened to half hour. By the time I got food I had little time to communicate with my pickup. Food was horrible. I decided final contract could still be made using the WiFi at the Panama City Terminal. But they. Had no WiFi.

Quasheba C.

May 25, 2019

The staff is good at some point but at others they need to improve. Also there needs to be some earlier buses to destinations like Panama City

Jefroy A.

May 17, 2019

FlixBus

3.5/511,289 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Orlando and Panama City?

Stops in Orlando

A - Orlando Bus Station

B - Orlando RedCoach Station

C - Jet Set Express Terminal

D - Disney World

E - International Dr SuperTours Terminal

F - Seaworld Hotels

Stops in Panama City

A - Panama City Greyhound Bus Station

Frequently asked questions about traveling from Orlando to Panama City, US by bus

What is the distance between Orlando and Panama City?
What are the departure and arrival stations when taking the bus from Orlando to Panama City?
What are the best sights and things to do in Panama City?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/10

$106

11/11

$122

Today

$65

11/13

$96

11/14

$82

11/15

$85

11/16

$82

11/17

$66

The cheapest trip from Orlando to Panama City, US was searched and found on Nov 12, 2025 with a price of $65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Panama City, US, as early as possible.

You can expect to pay from $65 to $122 for a bus ticket from Orlando to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $66 which is on 2025-11-17.