Bus Tickets from Orlando to Panama City, US

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TodayAug 9
TomorrowAug 10
from US$63
MonAug 11
from US$58
TueAug 12
from US$55
WedAug 13
from US$54
ThuAug 14
from US$55
FriAug 15
from US$58
SatAug 16
from US$57

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 10 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: August 10 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 10 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: August 10 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: August 10 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 10 at
    Departure city: Orlando
    Departure location: The Florida Mall
    Arrival time: August 10 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 10:46 PM EDT.

Prices and availability are subject to change.

Accepted payments

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  • American Express
  • China Union Pay
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  • Google Pay

Bus Orlando to Panama City, US: Trip Overview

Average Ticket PriceUS$69
Average Bus Trip Duration9h 20m
Number of daily buses3
Earliest bus departure5:40am
Distance466 km
Latest bus departure12:45pm

Orlando to Panama City Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Panama City.

Bus service from Orlando to Panama City will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from Orlando, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Orlando - Panama City, US

  1. What is the distance between Orlando and Panama City?

    Orlando and Panama City are 454 km (282 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Orlando to Panama City?

    Buses departing from Orlando Bus Station in Orlando will take you to Panama City Greyhound Bus Station in Panama City.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-07
US$55
08-08
US$55
Today
US$68
08-10
US$55
08-11
US$50
08-12
US$47
08-13
US$46
08-14
US$47
busbud logoThe cheapest trip from Orlando to Panama City, US was searched and found on Aug 13, 2025 with a price of US$46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Panama City, US, as early as possible.

You can expect to pay from US$46 to US$84 for a bus ticket from Orlando to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$46 which is on 2025-08-13.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Panama City but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Orlando to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to Panama City.

Tune out to the fine sounds of your best music playlist on your bus trip from Orlando to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Orlando by bus?

Bus from Orlando to Panama City, US

Why choose Busbud?

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