Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Orlando Bus Station | Panama City Beach Station | CheapestFastest | ||||
 | Bus | Orlando Bus Station | Panama City Beach Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | The Florida Mall | Panama City Beach Station | No tags |
Last refresh of the prices: Yesterday at 1:59 PM EST.
Get from Orlando to Panama City
The journey takes about 9 hours 20 minutes, and with fares starting at just $71, it presents an excellent value for a comfortable ride.
Where are the popular stops in Orlando and Panama City?
Stops in Orlando
- A555 N John Young Pkwy, Orlando, FL 32805
- BRedCoach Station, 1777 McCoy Road, Orlando, FL 32809
- CJet Set Express Terminal, 3718 LB Mcleod Rd., 32805 Orlando, FL,, United States
- D
Disney World
Disney's All-Star Sports Resort, 1701 West Buena Vista Dr., Orlando, FL 32830 - E
International Dr SuperTours Terminal
5419 International Dr, Orlando, FL 32819, USA - F
Seaworld Hotels
10100 International Drive , Orlando, 32821
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
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Frequently asked questions about travelling from Orlando to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Panama City?
The cheapest bus tickets from Orlando to Panama City start from $71. The average price for this route is around $138. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Panama City?
The average bus travel time from Orlando to Panama City is 9h 20m, covering a distance of 467 km. The quickest bus can get you there in 8h 55m and is operated by FlixBus.
Which bus companies service the Orlando to Panama City route?
What are the earliest and latest departure times for the bus from Orlando to Panama City?
The earliest bus departs from Orlando to Panama City at 4:40am. And the latest bus departs at 1:50pm.
What are the CO₂ emissions for the bus trip from Orlando to Panama City?
A bus trip from Orlando to Panama City generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Orlando to Panama City?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Orlando to Panama City?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Orlando to Panama City?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Panama City?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Orlando to Panama City, US was searched and found on Dec 3, 2025 with a price of $102To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Panama City, US, as early as possible.
You can expect to pay from $102 to $313 for a bus ticket from Orlando to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-12-03.
