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- This trip is recommended because it is: Cheapest + FastestDeparture time: August 10 atDeparture city: Panama CityDeparture location: Panama City Beach StationArrival time: August 10 atDestination city: OrlandoDestination location: Orlando Bus StationOperated by: Greyhound Lines, Inc.
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Bus Panama City, US to Orlando: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Panama City Orlando recent customer reviews
I missed my flight because of your delayed and all they could say was cancel your fligh worst bus company
Rondagaye E.
It was delayed in tellasey from 10pm until 5 am
Paulette C.
Nice drivers
Jose P.
Panama City to Orlando Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Panama City to Orlando.
We make sure you can find a bus service from Panama City to Orlando from the most reliable bus companies operating this trip.
Discover how much the bus trip from Panama City to Orlando will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Panama City and Orlando?
Frequently asked questions for your trip Panama City, US - Orlando
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Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Orlando was searched and found on Aug 13, 2025 with a price of $43To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Orlando, as early as possible.
You can expect to pay from $43 to $66 for a bus ticket from Panama City, US to Orlando based on the last 2 days. You can expect to find the cheapest price for the trip at $43 which is on 2025-08-13.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Panama City to Orlando but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Orlando, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Panama City to Orlando will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Panama City to Orlando while indulging in miles on end of beautiful scenic views.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Panama City
Buses Leaving from Panama City
- Bus from Panama City to Long Beach
- Bus Panama City - Miami
- Panama City - San Jose
- Bus from Panama City to Atlanta
- Bus Panama City - Orlando
- Panama City - Tallahassee
- Bus from Panama City to Tampa
- Bus Panama City - Fort Lauderdale
- Panama City - Jacksonville
- Bus from Panama City to Biloxi
- Bus Panama City - New York City
- Panama City - Gainesville
- Bus from Panama City to New Orleans
- Bus Panama City - Fort Walton Beach
- Panama City - Dothan
Buses Going to Panama City
- Bus from Miami to Panama City
- Bus Tallahassee - Panama City
- Atlanta - Panama City
- Bus from Tampa to Panama City
- Bus Chicago - Panama City
- San Jose - Panama City
- Bus from Orlando to Panama City
- Bus Jacksonville - Panama City
- Fort Lauderdale - Panama City
- Bus from Houston to Panama City
- Bus Dothan - Panama City
- New Orleans - Panama City
- Bus from New York City to Panama City
- Bus Birmingham - Panama City
- Fort Walton Beach - Panama City
Popular Buses Connecting Orlando
Buses Leaving from Orlando
- Bus from Orlando to Melbourne
- Bus Orlando - Tampa
- Orlando - Jacksonville
- Bus from Orlando to Jacksonville
- Bus Orlando - Daytona Beach
- Orlando - Ocala
- Bus from Orlando to Gainesville
- Bus Orlando - Bradenton
- Orlando - New York City
- Bus from Orlando to Tallahassee
- Bus Orlando - Port Saint Lucie
- Orlando - West Palm Beach
- Bus from Orlando to Pompano Beach
Buses Going to Orlando
- Bus from Tampa to Orlando
- Bus Atlanta - Orlando
- Chicago - Orlando
- Bus from Norman to Orlando
- Bus Houston - Orlando
- Ocala - Orlando
- Bus from Hollywood to Orlando
- Bus Gainesville - Orlando
- Bradenton - Orlando
- Bus from Jacksonville to Orlando
- Bus New York City - Orlando
- Pompano Beach - Orlando
- Bus from Port Saint Lucie to Orlando
- Bus Naples - Orlando