How much is the bus ticket from Panama City to San Jose?

The cheapest bus tickets from Panama City to San Jose start from $156. The average price for this route is around $252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Panama City to San Jose?

The average bus trip duration from Panama City to San Jose is 2d 9h, covering a distance of 2115 miles (3412 km). The quickest bus can get you there in 2d 9h and is operated by Greyhound .

Which bus companies service the Panama City to San Jose route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the bus from Panama City to San Jose?

The earliest bus departs from Panama City to San Jose at 12:50pm. And the latest bus departs at 9:40pm.

What are the CO₂ emissions for the bus trip from Panama City to San Jose?

A bus trip from Panama City to San Jose generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Panama City to San Jose from $149 | Refundable Tickets

Previously seen trips

Next departures for Panama City to San Jose on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	7:30pm	Panama City Beach Station	2d 11h	5:25am	Diridon Station	No tags
FlixBus + Greyhound	Bus	1:55pm	Panama City Beach Station	2d 18h	6:25am	Diridon Station	No tags
Greyhound + FlixBus	Bus	1:55pm	Panama City Beach Station	2d 17h	5:25am	Diridon Station	No tags
FlixBus + Greyhound	Bus	1:55pm	Panama City Beach Station	2d 17h	5:25am	Diridon Station	No tags
	Bus	12:50pm	Panama City Beach Station	2d 18h	5:25am	Diridon Station	No tags

Get from Panama City to San Jose

This route is served by bus only

The journey takes about 2 days, 9 hours 45 minutes and with fares starting at just $156, it presents an excellent value for a comfortable ride.

1bus per day

2d 9hAverage Duration

2115 milesDistance

85kgCO₂ emissions

Where are the popular stops in Panama City and San Jose?

Stops in Panama City

A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401

Stops in San Jose

A
Diridon Station
65 Cahill St., San Jose, CA 95110
Visit page
B
Santiago Express San Jose
440 S King rd , an Jose CA 95116
Visit page
C
1118 E William St
1118 E William St, San Jose, CA 95116, USA
D
San Jose Bus Stop
100 W San Carlos St, San Jose, CA 95113, USA
E
Tamien Station
Guadalupe Fwy, San Jose, CA 95110, USA
F
Diridon Station
65 Cahill St, San Jose, CA 95110, USA

Compare bus companies

Greyhound

3.5/587,418 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Panama City, US to San Jose, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Panama City to San Jose?
The cheapest bus tickets from Panama City to San Jose start from $156. The average price for this route is around $252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to San Jose?
The average bus trip duration from Panama City to San Jose is 2d 9h, covering a distance of 2115 miles (3412 km). The quickest bus can get you there in 2d 9h and is operated by Greyhound.
Which bus companies service the Panama City to San Jose route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Panama City to San Jose?
The earliest bus departs from Panama City to San Jose at 12:50pm. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Panama City to San Jose?
A bus trip from Panama City to San Jose generates an estimated 85 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12/04

$550

12/05

No data

Today

No data

12/07

No data

12/08

No data

12/09

$306

12/10

No data

12/11

$163

The cheapest trip from Panama City, US to San Jose, US was searched and found on Dec 11, 2025 with a price of $163

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to San Jose, US, as early as possible.

You can expect to pay from $163 to $550 for a bus ticket from Panama City, US to San Jose, US based on the last 2 days. You can expect to find the cheapest price for the trip at $163 which is on 2025-12-11.