Bus Tickets from San Francisco, US to Chicago

Next departures

Next departures for San Francisco to Chicago on October 1
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
Downtown Greyhound StationCheapest
Greyhound Lines, Inc.
San Francisco Bus Station
Downtown Greyhound StationFastest
Amtrak
Mission St & Fremont St
Chicago (Union Station), ILNo tags
FlixBus + Greyhound Lines, Inc.
409 Townsend St, SF
Downtown Greyhound StationNo tags
Greyhound Lines, Inc.
San Francisco Bus Station
537-517 W. Jackson BlvdNo tags

Last refresh of the prices: Yesterday at 5:16 PM PDT.

Accepted payments

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Bus San Francisco, US to Chicago: Trip Overview

Average ticket price$242
Average bus trip duration2d 16h
Number of daily buses12
Earliest bus departure6:30am
Distance1849 miles (2982 km)
Latest bus departure11:25pm

San Francisco to Chicago Bus

Busbud helps you find a bus from San Francisco to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Francisco to Chicago.

From cheap bus tickets to more luxurious buses traveling from San Francisco to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Francisco, US - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/28
No data
09/29
$139
Today
$145
10/01
$220
10/02
$151
10/03
No data
10/04
No data
10/05
No data
busbud logoThe cheapest trip from San Francisco, US to Chicago was searched and found on Sep 29, 2025 with a price of $139

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to Chicago, as early as possible.

You can expect to pay from $139 to $2,472 for a bus ticket from San Francisco, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $151 which is on 2025-10-02.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and Chicago!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Francisco to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to Chicago that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Francisco to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to San Francisco, US by bus?

Bus from Chicago to San Francisco, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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