Bus Tickets from San Diego, CA, US to San Francisco, US

Next departures

Next departures for San Diego to San Francisco on September 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Amtrak
Santa Fe Depot
Mission St & Fremont StCheapest
Greyhound Lines, Inc.
Greyhound Bus Stop
San Francisco Bus StationFastest
FlixBus
San Diego (Old Town-FlixBus)
409 Townsend St, SFNo tags
FlixBus + Greyhound Lines, Inc.
San Diego (Old Town-FlixBus)
San Francisco Bus StationNo tags
FlixBus
UCSD Health La Jolla Station
409 Townsend St, SFNo tags

Last refresh of the prices: Today at 2:28 AM PDT.

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Compare 2 ways to go from San Diego to San Francisco.

Bus
Average Price$56 - $189Average Duration14h 35m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$69 - $341Average Duration13h 44m
67kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from San Diego to San Francisco

Among the sustainable travel choices, the train stands out as the good way to reach San Francisco. The journey takes about 13 hours 44 minutes and with fares starting at just $69, it presents an excellent value for a comfortable ride.

11train per day
13h 44mAverage Duration
$69Cheapest ticket
67kgCO₂ emissions

Bus San Diego, CA, US to San Francisco, US: Trip Overview

Average ticket price$73
Average bus trip duration14h 35m
Number of daily buses12
Earliest bus departure6:45am
Distance457 miles (737 km)
Latest bus departure9:25pm

San Diego to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Diego to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to San Francisco from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Francisco from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Diego, CA, US - San Francisco, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/25
$99
09/26
$181
Today
$77
09/28
$102
09/29
$67
09/30
$62
10/01
$52
10/02
$55
busbud logoThe cheapest trip from San Diego, CA, US to San Francisco, US was searched and found on Oct 1, 2025 with a price of $52

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to San Francisco, US, as early as possible.

You can expect to pay from $52 to $212 for a bus ticket from San Diego, CA, US to San Francisco, US based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-10-01.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to San Francisco, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to San Francisco.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to San Francisco while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to San Diego, CA, US by bus?

Bus from San Francisco, US to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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