Next departures to Chicago
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: FastestDeparture time: August 12 atDeparture city: San FranciscoDeparture location: Mission St & Fremont StArrival time: August 14 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: Amtrak
Vehicle: BusDuration: - Departure time: August 12 atDeparture city: San FranciscoDeparture location: Mission St & Fremont StArrival time: August 14 atDestination city: ChicagoDestination location: Chicago (Union Station), ILOperated by: AmtrakVehicle: BusDuration:
- Departure time: August 12 atDeparture city: San FranciscoDeparture location: San Francisco Bus StationArrival time: August 15 atDestination city: ChicagoDestination location: Downtown Greyhound StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Today at 4:14 AM PDT.
Prices and availability are subject to change.
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Bus San Francisco, US to Chicago: Trip Overview
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San Francisco to Chicago Bus
Busbud helps you find a bus from San Francisco to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from San Francisco to Chicago.
From cheap bus tickets to more luxurious buses travelling from San Francisco to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Francisco and Chicago?
Frequently asked questions on the trip San Francisco, US - Chicago
What is the distance between San Francisco and Chicago?
The distance between San Francisco and Chicago is approximately 2987 km (1852 miles).
What are the departure and arrival locations for buses traveling from San Francisco to Chicago?
Buses departing from Hyde/Beach (Fisherman's Wharf) in San Francisco will take you to Downtown Greyhound Station in Chicago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Francisco, US to Chicago was searched and found on Aug 9, 2025 with a price of US$127To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco, US to Chicago, as early as possible.
You can expect to pay from US$127 to US$2,805 for a bus ticket from San Francisco, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$185 which is on 2025-08-15.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and Chicago!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Francisco to Chicago.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to Chicago that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from San Francisco to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting San Francisco
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Buses Going to San Francisco
Popular Buses Connecting Chicago
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Buses Going to Chicago
Popular routes in this country
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