Bus Panama City, US to Big Pine Key: Trip Overview
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Panama City to Big Pine Key Bus
Busbud helps you find a bus from Panama City to Big Pine Key. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Panama City to Big Pine Key from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Big Pine Key from Panama City, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Panama City, US - Big Pine Key
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Big Pine Key was searched and found on Aug 8, 2025 with a price of $123To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Big Pine Key, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Big Pine Key!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Big Pine Key, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Panama City to Big Pine Key.
Make a music playlist for your bus ride from Panama City to Big Pine Key, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Panama City
Buses Leaving from Panama City
- Bus from Panama City to Long Beach
- Bus Panama City - Miami
- Panama City - San Jose
- Bus from Panama City to Atlanta
- Bus Panama City - Orlando
- Panama City - Tallahassee
- Bus from Panama City to Tampa
- Bus Panama City - Fort Lauderdale
- Panama City - Jacksonville
- Bus from Panama City to Biloxi
- Bus Panama City - New York City
- Panama City - Gainesville
- Bus from Panama City to New Orleans
- Bus Panama City - Fort Walton Beach
- Panama City - Dothan
Buses Going to Panama City
- Bus from Miami to Panama City
- Bus Tallahassee - Panama City
- Atlanta - Panama City
- Bus from Tampa to Panama City
- Bus Chicago - Panama City
- San Jose - Panama City
- Bus from Orlando to Panama City
- Bus Jacksonville - Panama City
- Fort Lauderdale - Panama City
- Bus from Houston to Panama City
- Bus Dothan - Panama City
- New Orleans - Panama City
- Bus from New York City to Panama City
- Bus Birmingham - Panama City
- Fort Walton Beach - Panama City
Popular Buses Connecting Big Pine Key
Buses Leaving from Big Pine Key
- Bus from Big Pine Key to Miami
- Bus Big Pine Key - Tampa
- Big Pine Key - Orlando
- Bus from Big Pine Key to Philadelphia
- Bus Big Pine Key - Allentown
- Big Pine Key - Fort Lauderdale
- Bus from Big Pine Key to Key West
- Bus Big Pine Key - Chicago
- Big Pine Key - Fort Myers
- Bus from Big Pine Key to Jacksonville
- Bus Big Pine Key - Atlanta
- Big Pine Key - Gadsden
- Bus from Big Pine Key to Marathon
- Bus Big Pine Key - Washington
- Big Pine Key - Panama City
Buses Going to Big Pine Key
- Bus from Miami to Big Pine Key
- Bus Key West - Big Pine Key
- Tampa - Big Pine Key
- Bus from Key Largo to Big Pine Key
- Bus Marathon - Big Pine Key
- Fort Lauderdale - Big Pine Key
- Bus from Arcadia to Big Pine Key
- Bus Orlando - Big Pine Key
- Philadelphia - Big Pine Key
- Bus from Lakeland to Big Pine Key
- Bus Boston - Big Pine Key
- Charlottesville - Big Pine Key
- Bus from West Palm Beach to Big Pine Key
- Bus St. Petersburg - Big Pine Key
- Chicago - Big Pine Key