Bus Tickets from Panama City, US to Big Pine Key

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Bus Panama City, US to Big Pine Key: Trip Overview

Average Ticket PriceUS$130
Average Bus Trip Duration23h 55m
Number of daily buses2
Earliest bus departure7:40am
Distance752 km
Latest bus departure12:50pm

Panama City to Big Pine Key Bus

Busbud helps you find a bus from Panama City to Big Pine Key. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to Big Pine Key from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Big Pine Key from Panama City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Panama City, US - Big Pine Key

  1. What is the distance between Panama City and Big Pine Key?

    The distance between Panama City and Big Pine Key is around 745 km (462 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-08
US$123
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busbud logoThe cheapest trip from Panama City, US to Big Pine Key was searched and found on Aug 8, 2025 with a price of US$123

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Big Pine Key, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Big Pine Key!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Big Pine Key, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Panama City to Big Pine Key.

Make a music playlist for your bus ride from Panama City to Big Pine Key, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Panama City, US by bus?

Bus from Panama City, US to Big Pine Key

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