Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Gateway Station | Des Moines (Subway) | CheapestFastest |
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Bus St. Louis to Des Moines: Trip Overview
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St. Louis to Des Moines Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St. Louis to Des Moines.
We make sure you can find a bus service from St. Louis to Des Moines from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from St. Louis to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in St. Louis and Des Moines?
Frequently asked questions on the trip St. Louis - Des Moines
What is the travel distance from St. Louis to Des Moines?
It's about 441 km (273 miles) from St. Louis to Des Moines.
What are the departure and arrival locations for buses traveling from St. Louis to Des Moines?
Buses departing from Gateway Station in St. Louis will take you to Jefferson/Trailways Depot in Des Moines.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St. Louis to Des Moines but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to Des Moines, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Des Moines that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from St. Louis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Top travelled bus routes
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Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
- Bus from St. Louis to New Orleans
- Bus St. Louis - Kansas City
- St. Louis - Kansas City
- Bus from St. Louis to Buffalo
- Bus St. Louis - Austin
- St. Louis - Nashville
- Bus from St. Louis to Indianapolis
- Bus St. Louis - Columbia
- St. Louis - Chicago
- Bus from St. Louis to Houston
- Bus St. Louis - Champaign
- St. Louis - Lawrence
- Bus from St. Louis to Murfreesboro
- Bus St. Louis - Rockford
- St. Louis - Carbondale
Buses Going to St. Louis
- Bus from Manchester to St. Louis
- Bus Manchester - St. Louis
- New Orleans - St. Louis
- Bus from Atlanta to St. Louis
- Bus Indianapolis - St. Louis
- Burlington - St. Louis
- Bus from Chicago to St. Louis
- Bus Pasco - St. Louis
- Springfield - St. Louis
- Bus from Cheyenne to St. Louis
- Bus Columbia - St. Louis
- Lafayette - St. Louis
- Bus from Memphis to St. Louis
- Bus Miami - St. Louis
- Champaign - St. Louis
Popular Buses Connecting Des Moines
Buses Leaving from Des Moines
- Bus from Des Moines to Iowa City
- Bus Des Moines - Washington
- Des Moines - Omaha
- Bus from Des Moines to Denver
- Bus Des Moines - Cedar Rapids
- Des Moines - Chicago
- Bus from Des Moines to Jackson
- Bus Des Moines - Ames
- Des Moines - Keokuk
- Bus from Des Moines to San Diego
- Bus Des Moines - Las Vegas
- Des Moines - Clear Lake
- Bus from Des Moines to Madison
- Bus Des Moines - Lubbock
- Des Moines - Latimer
Buses Going to Des Moines
- Bus from Washington to Des Moines
- Bus Chicago - Des Moines
- Minneapolis - Des Moines
- Bus from Las Vegas to Des Moines
- Bus Staples - Des Moines
- Iowa City - Des Moines
- Bus from Vermillion to Des Moines
- Bus Waterloo - Des Moines
- Newark - Des Moines
- Bus from Los Angeles to Des Moines
- Bus Latimer - Des Moines
- Eau Claire - Des Moines
- Bus from Bloomington to Des Moines
- Bus Ottumwa - Des Moines
- Austin - Des Moines
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Baton Rouge to New Orleans
- Bus Los Angeles - San Francisco
- Miami - Orlando
- Bus from Las Vegas to Los Angeles
- Bus Los Angeles - San Diego
- Atlanta - Savannah