Bus Tickets from Des Moines to St. Louis

Next departures

Next departures for Des Moines to St. Louis on September 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Des Moines (Subway)
Gateway StationCheapestFastest

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Des Moines to St. Louis: Trip Overview

Average Ticket PriceUS$90
Average Bus Trip Duration17h 35m
Number of daily buses1
Earliest bus departure5:30am
Distance439 km
Latest bus departure8:15am

Des Moines to St. Louis Bus

Busbud helps you find a bus from Des Moines to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to St. Louis.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Des Moines - St. Louis

  1. What is the distance between Des Moines and St. Louis?

    The distance covered from Des Moines to St. Louis is 441 km (273 miles).

  2. What are the departure and arrival locations for buses traveling from Des Moines to St. Louis?

    Buses traveling this route start their trip at Jefferson/Trailways Depot, in Des Moines, and end it at Gateway Station, in St. Louis.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and St. Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to St. Louis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from St. Louis to Des Moines

Why choose Busbud?

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