Bus Tickets from Lafayette, IN to St. Louis

Next departures

Next departures for Lafayette to St. Louis on October 30
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Lafayette Bus Stop
Gateway StationCheapest
Greyhound Lines, Inc.
Lafayette Bus Stop
Gateway StationFastest
Greyhound Lines, Inc. + FlixBus
Lafayette Bus Stop
Gateway StationNo tags
Greyhound Lines, Inc. + FlixBus
Lafayette Bus Stop
Gateway StationNo tags

Last refresh of the prices: Yesterday at 1:33 AM EDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Get from Lafayette to St. Louis

busbud logoThis route is served by bus only

The journey takes about 9 hours, and with fares starting at just US$36, it presents an excellent value for a comfortable ride.

4bus per day
9hAverage Duration
348 kmDistance
9kgCO₂ emissions

Bus Lafayette, IN to St. Louis: Trip Overview

Average Ticket PriceUS$60
Average Bus Trip Duration9h
Number of daily buses4
Earliest bus departure9:35am
Distance347 km
Latest bus departure9:25pm

Lafayette to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Lafayette to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Lafayette to St. Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Lafayette, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Lafayette, IN - St. Louis

  1. What is the distance between Lafayette and St. Louis?

    The distance covered from Lafayette to St. Louis is 354 km (220 miles).

  2. What are the departure and arrival locations for buses traveling from Lafayette to St. Louis?

    Buses traveling this route start their trip at CityBus Center, in Lafayette, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-27
US$52
10-28
US$64
Today
US$53
10-30
US$37
10-31
No data
11-01
US$46
11-02
No data
11-03
No data
busbud logoThe cheapest trip from Lafayette, IN to St. Louis was searched and found on Oct 30, 2025 with a price of US$37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lafayette, IN to St. Louis, as early as possible.

You can expect to pay from US$37 to US$124 for a bus ticket from Lafayette, IN to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$37 which is on 2025-10-30.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Lafayette to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Lafayette to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Lafayette to St. Louis.

Make a music playlist for your bus ride from Lafayette to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Lafayette, IN by bus?

Bus from St. Louis to Lafayette, IN

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Lafayette

Buses Leaving from Lafayette

Buses Going to Lafayette

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis