Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Amtrak Station | Gateway Station | CheapestFastest | |||||
| Amtrak Station | Gateway Station | No tags | |||||
 | Houston Bus Station | Gateway Station | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Houston Bus Station | Gateway Station | No tags | |||||
 | Downtown Gray & Smith | Gateway Station | No tags |
Last refresh of the prices: Yesterday at 10:22 PM CST.
Get from Houston to St. Louis
The journey takes about 1 day, 1 hour 30 minutes, and with fares starting at just $171, it presents an excellent value for a comfortable ride.
Where are the popular stops in Houston and St. Louis?
Stops in Houston
- A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA - B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002 - C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA - D7011 Harrisburg Blvd, Houston, TX 77011, USA
- E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA - F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
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Frequently asked questions about travelling from Houston, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to St. Louis?
The cheapest bus tickets from Houston to St. Louis start from $171. The average price for this route is around $241. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to St. Louis?
The average bus travel time from Houston to St. Louis is 1d 1h, covering a distance of 1099 km. The quickest bus can get you there in 18h 25m and is operated by Amtrak.
Which bus companies service the Houston to St. Louis route?
Several major bus companies operate on this route with 22 buses available per day, including services from Greyhound, FlixBus, Amtrak, Valley Transit.
What are the earliest and latest departure times for the bus from Houston to St. Louis?
The earliest bus departs from Houston to St. Louis at 12:05am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to St. Louis?
A bus trip from Houston to St. Louis generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Houston to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5627 reviews.
Which bus company has the best Wi-Fi from Houston to St. Louis?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Houston to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Houston, US to St. Louis was searched and found on Dec 11, 2025 with a price of $178To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to St. Louis, as early as possible.
You can expect to pay from $178 to $604 for a bus ticket from Houston, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $178 which is on 2025-12-11.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
