Bus Tickets from Des Moines to San Diego, CA, US

Next departures

Next departures for Des Moines to San Diego on September 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Des Moines (Subway)
Greyhound Bus StopCheapest
Greyhound Lines, Inc. + FlixBus
Des Moines (Subway)
UCSD Health La Jolla StationFastest
Greyhound Lines, Inc. + FlixBus
Des Moines (Subway)
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc. + FlixBus
Des Moines (Subway)
Downtown SD (Seaport)No tags

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
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  • Google Pay

Bus Des Moines to San Diego, CA, US: Trip Overview

Average Ticket PriceUS$292
Average Bus Trip Duration2d 14h
Number of daily buses4
Earliest bus departure5:30am
Distance2295 km

Des Moines to San Diego Bus

Busbud helps you find a bus from Des Moines to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to San Diego from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Des Moines to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Des Moines - San Diego, CA, US

  1. How far is Des Moines from San Diego?

    It's about 2302 km (1427 miles) from Des Moines to San Diego.

  2. What are the departure and arrival locations for buses traveling from Des Moines to San Diego?

    Buses traveling this route start their trip at Jefferson/Trailways Depot, in Des Moines, and end it at Mission Valley Sheraton, in San Diego.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and San Diego!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to San Diego, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to San Diego that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Des Moines to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Des Moines by bus?

Bus from San Diego, CA, US to Des Moines

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