Bus from Columbia, MO to St. Louis: Tickets & Schedules

Next bus departures

Next departures for Columbia to St. Louis on December 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Midway Truck Plaza Bus Stop
Gateway StationCheapest
Greyhound Lines, Inc.Bus
Midway Truck Plaza Bus Stop
Gateway StationFastest
Greyhound Lines, Inc.Bus
Midway Truck Plaza Bus Stop
Gateway StationNo tags
Greyhound Lines, Inc.Bus
Columbia Wabash Station
Gateway StationNo tags
Greyhound Lines, Inc.Bus
Columbia Wabash Station
Gateway StationNo tags

Last refresh of the prices: Yesterday at 8:48 PM CST.

Get from Columbia to St. Louis

This route is served by bus only

The journey takes about 2 hours 50 minutes, and with fares starting at just $39, it presents an excellent value for a comfortable ride.

5bus per day
2h 50mAverage Duration
198 kmDistance
5kgCO₂ emissions

Frequently asked questions about travelling from Columbia, MO to St. Louis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Columbia to St. Louis?

    The cheapest bus tickets from Columbia to St. Louis start from $39. The average price for this route is around $51. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Columbia to St. Louis?

    The average bus travel time from Columbia to St. Louis is 2h 50m, covering a distance of 198 km. The quickest bus can get you there in 2h 15m and is operated by Greyhound.

  3. Which bus companies service the Columbia to St. Louis route?

    Several major bus companies operate on this route with 5 buses available per day.

  4. What are the earliest and latest departure times for the bus from Columbia to St. Louis?

    The earliest bus departs from Columbia to St. Louis at 8:30am. And the latest bus departs at 8:35pm.

  5. What are the CO₂ emissions for the bus trip from Columbia to St. Louis?

    A bus trip from Columbia to St. Louis generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-02
$38
12-03
$42
Today
$36
12-05
$38
12-06
$31
12-07
$34
12-08
$31
12-09
$31
busbud logoThe cheapest trip from Columbia, MO to St. Louis was searched and found on Dec 6, 2025 with a price of $31

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to St. Louis, as early as possible.

You can expect to pay from $31 to $101 for a bus ticket from Columbia, MO to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $31 which is on 2025-12-06.

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