Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Santiago Tuxtla, Santiago Tuxtla Ver. | TAPO | CheapestFastest | |||||
| Santiago Tuxtla, Santiago Tuxtla Ver. | TAPO | No tags | |||||
| Santiago Tuxtla, Santiago Tuxtla Ver. | TAPO | No tags | |||||
| Santiago Tuxtla, Santiago Tuxtla Ver. | Terminal del Norte | No tags |
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Bus Santiago Tuxtla to Mexico City: Trip Overview
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Santiago Tuxtla to Mexico City Bus
Busbud helps you find a bus from Santiago Tuxtla to Mexico City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Santiago Tuxtla to Mexico City will be provided by the most trusted bus companies.
Discover how much the bus trip from Santiago Tuxtla to Mexico City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Santiago Tuxtla - Mexico City
What is the travel distance from Santiago Tuxtla to Mexico City?
The distance covered from Santiago Tuxtla to Mexico City is 418 km (259 miles).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santiago Tuxtla to Mexico City was searched and found on Aug 29, 2025 with a price of US$57To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago Tuxtla to Mexico City, as early as possible.
You can expect to pay from US$57 to US$66 for a bus ticket from Santiago Tuxtla to Mexico City based on the last 2 days. You can expect to find the cheapest price for the trip at US$66 which is on 2025-09-01.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santiago Tuxtla and Mexico City!
Much more than a mere vehicle taking you from Santiago Tuxtla to Mexico City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santiago Tuxtla to Mexico City will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Santiago Tuxtla to Mexico City while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
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Popular Buses Connecting Santiago Tuxtla
Buses Leaving from Santiago Tuxtla
- Bus from Santiago Tuxtla to Lerdo de Tejada
- Bus Santiago Tuxtla - Ángel R. Cabada
- Santiago Tuxtla - Alvarado
- Bus from Santiago Tuxtla to San Andrés Tuxtla
- Bus Santiago Tuxtla - Catemaco
- Santiago Tuxtla - Córdoba
- Bus from Santiago Tuxtla to Puebla
- Bus Santiago Tuxtla - Mexico City
- Santiago Tuxtla - Xalapa
- Bus from Santiago Tuxtla to Veracruz
- Bus Santiago Tuxtla - Ciudad del Carmen
Buses Going to Santiago Tuxtla
- Bus from Veracruz to Santiago Tuxtla
- Bus Alvarado - Santiago Tuxtla
- Puebla - Santiago Tuxtla
- Bus from José Cardel to Santiago Tuxtla
- Bus Ángel R. Cabada - Santiago Tuxtla
- Catemaco - Santiago Tuxtla
- Bus from Mexico City to Santiago Tuxtla
- Bus San Andrés Tuxtla - Santiago Tuxtla
- Xalapa - Santiago Tuxtla
- Bus from Córdoba to Santiago Tuxtla
- Bus Lerdo de Tejada - Santiago Tuxtla
Popular Buses Connecting Mexico City
Buses Leaving from Mexico City
- Bus from Mexico City to Cancún
- Bus Mexico City - Centro
- Mexico City - Denver
- Bus from Mexico City to Tulum
- Bus Mexico City - Toronto
- Mexico City - Los Angeles
- Bus from Mexico City to Puerto Escondido
- Bus Mexico City - Santiago de Querétaro
- Mexico City - Guadalajara
- Bus from Mexico City to Puerto Vallarta
- Bus Mexico City - Morelia
- Mexico City - Cuernavaca
- Bus from Mexico City to Zihuatanejo
- Bus Mexico City - Veracruz
- Mexico City - Taxco
Buses Going to Mexico City
- Bus from Chicago to Mexico City
- Bus Miami - Mexico City
- Austin - Mexico City
- Bus from San Juan to Mexico City
- Bus Temple - Mexico City
- Dixon - Mexico City
- Bus from San Miguel de Allende to Mexico City
- Bus Oaxaca - Mexico City
- Puebla - Mexico City
- Bus from Puerto Vallarta to Mexico City
- Bus Guadalajara - Mexico City
- Cancún - Mexico City
- Bus from Guanajuato to Mexico City
- Bus Santiago de Querétaro - Mexico City
- Veracruz - Mexico City
Popular routes in this country
- Bus from Mexico City to San Miguel de Allende
- Bus Mexico City - Puebla
- Mérida - Cancún
- Bus from Playa del Carmen to Tulum
- Bus Cancún - Chichén-Itzá
- Mexico City - Acapulco
- Bus from Mazatlán to Puerto Vallarta
- Bus Puerto Vallarta - Rincón de Guayabitos
- Puerto Vallarta - Mazatlán
- Bus from San José del Cabo to La Paz
- Bus Cancún - Valladolid
- Puerto Vallarta - San Patricio
- Bus from Mexico City to Ixmiquilpan
- Bus Cancún - Bacalar
- Mexico City - Guanajuato