Bus Tickets from Mexico City to Santiago Tuxtla

Next departures

Next departures for Mexico City to Santiago Tuxtla on October 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AU
TAPO
Santiago Tuxtla, Santiago Tuxtla Ver.Cheapest
ADO
TAPO
Santiago Tuxtla, Santiago Tuxtla Ver.Fastest
ADO
TAPO
Santiago Tuxtla, Santiago Tuxtla Ver.No tags
AU
Terminal del Norte
Santiago Tuxtla, Santiago Tuxtla Ver.No tags
ADO
TAPO
Santiago Tuxtla, Santiago Tuxtla Ver.No tags

Last refresh of the prices: Last Tuesday at 12:21 PM CST.

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Bus Mexico City to Santiago Tuxtla: Trip Overview

Average Ticket PriceUS$76
Average Bus Trip Duration9h
Number of daily buses5
Earliest bus departure11:00am
Distance419 km
Latest bus departure11:59pm

Mexico City to Santiago Tuxtla Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mexico City to Santiago Tuxtla.

Bus service from Mexico City to Santiago Tuxtla will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santiago Tuxtla from Mexico City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Mexico City - Santiago Tuxtla

  1. How far is Mexico City from Santiago Tuxtla?

    It's about 418 km (259 miles) from Mexico City to Santiago Tuxtla.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-01
US$67
10-02
US$67
Today
US$57
10-04
US$66
10-05
US$57
10-06
No data
10-07
No data
10-08
US$67
busbud logoThe cheapest trip from Mexico City to Santiago Tuxtla was searched and found on Oct 5, 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to Santiago Tuxtla, as early as possible.

You can expect to pay from US$57 to US$67 for a bus ticket from Mexico City to Santiago Tuxtla based on the last 2 days. You can expect to find the cheapest price for the trip at US$57 which is on 2025-10-05.

Usually ADO will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mexico City to Santiago Tuxtla but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Mexico City to Santiago Tuxtla, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexico City to Santiago Tuxtla.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mexico City to Santiago Tuxtla.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Mexico City by bus?

Bus from Santiago Tuxtla to Mexico City

Why choose Busbud?

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