Bus Tickets from Mezcales to Guadalajara, MX

TodayAug 5
from US$41
TomorrowAug 6
from US$41
ThuAug 7
from US$41
FriAug 8
SatAug 9
SunAug 10
MonAug 11
TueAug 12

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: August 6 at
    Departure city: Mezcales
    Departure location: Pacífico - Revolución
    Arrival time: August 6 at
    Destination city: Guadalajara
    Destination location: Nueva Central Camionera, Estación Central de Autobuses de Guadalajara
    Operated by: PacificoPacifico
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Mezcales
    Departure location: Pacífico - Revolución
    Arrival time: August 6 at
    Destination city: Guadalajara
    Destination location: Nueva Central Camionera, Estación Central de Autobuses de Guadalajara
    Operated by: PacificoPacifico
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Mezcales
    Departure location: Pacífico - Revolución
    Arrival time: August 6 at
    Destination city: Guadalajara
    Destination location: Nueva Central Camionera, Estación Central de Autobuses de Guadalajara
    Operated by: FuturaFutura
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Mezcales
    Departure location: Pacífico - Revolución
    Arrival time: August 6 at
    Destination city: Guadalajara
    Destination location: Nueva Central Camionera, Estación Central de Autobuses de Guadalajara
    Operated by: ChihuahuensesChihuahuenses
    Vehicle: BusDuration:
  • Departure time: August 6 at
    Departure city: Mezcales
    Departure location: Pacífico - Revolución
    Arrival time: August 6 at
    Destination city: Guadalajara
    Destination location: Nueva Central Camionera, Estación Central de Autobuses de Guadalajara
    Operated by: Pacifico + Norte de Sonora
    Pacifico + Norte de Sonora
    Vehicle: BusDuration:

Last refresh of the prices: Today at 12:33 AM CST.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Mezcales to Guadalajara

Bus
Average PriceUS$46 - US$61Average Duration5h 20m
5kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$13 - US$26Average Duration3h 30m
9kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Mezcales to Guadalajara

Among the sustainable travel choices, the carpool stands out as a good way to reach Guadalajara. The journey takes about 3 hours 30 minutes, and with fares starting at just US$13, it presents an excellent value for a comfortable ride.

15carpool per day
3h 30mAverage Duration
US$13Cheapest ticket
9kgCO₂ emissions

Bus Mezcales to Guadalajara, MX: Trip Overview

Average Ticket PriceUS$49
Average Bus Trip Duration5h 20m
Number of daily buses23
Earliest bus departure12:14am
Distance208 km
Latest bus departure11:32pm

Mezcales to Guadalajara Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mezcales to Guadalajara.

Bus service from Mezcales to Guadalajara will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Mezcales to Guadalajara, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Mezcales - Guadalajara, MX

  1. What is the distance between Mezcales and Guadalajara?

    It's about 197 km (123 miles) from Mezcales to Guadalajara.

  2. What are the departure and arrival locations for buses traveling from Mezcales to Guadalajara?

    Buses departing from Parada de Autobuses de Mezcales in Mezcales will take you to Nueva Central in Guadalajara.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-03
US$35
08-04
US$35
Today
US$35
08-06
US$35
08-07
US$35
08-08
No data
08-09
No data
08-10
No data
busbud logoThe cheapest trip from Mezcales to Guadalajara, MX was searched and found on Aug 5, 2025 with a price of US$35

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mezcales to Guadalajara, MX, as early as possible.

You can expect to pay from US$35 to US$45 for a bus ticket from Mezcales to Guadalajara, MX based on the last 2 days. You can expect to find the cheapest price for the trip at US$35 which is on 2025-08-06.

Usually AUTOBUSES EXPRESO FUTURA will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mezcales to Guadalajara but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Mezcales to Guadalajara, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mezcales to Guadalajara that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mezcales to Guadalajara.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Mezcales by bus?

Bus from Mezcales to Guadalajara, MX

Why choose Busbud?

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Popular Buses Connecting Mezcales

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Popular Buses Connecting Guadalajara

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