Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Nogales Av. Alvaro Obregon | Central Camionera Poniente | Cheapest | ||||
| Bus | Nogales Av. Alvaro Obregon | Central Camionera Poniente | Fastest | ||||
| Bus | Nuevo Vallarta, Nayarit | Central Camionera Poniente | No tags | ||||
| Bus | Nuevo Vallarta, Nayarit | Central Camionera Poniente | No tags | ||||
| Bus | Nuevo Vallarta, Nayarit | Central Camionera Poniente | No tags |
Last refresh of the prices: Last Sunday at 11:03 PM CST.
Compare 2 ways to go from Mezcales to Guadalajara
Among the sustainable travel choices, the carpool stands out as the good way to reach Guadalajara. The journey takes about 3 hours 30 minutes and with fares starting at just $15, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$48 - $65 | Average Duration4h 18m | 5kg CO₂e | ||
Carpool | Average Price$15 - $28 | Average Duration3h 30m | 9kg CO₂e |
Where are the popular stops in Mezcales and Guadalajara?
Stops in Mezcales
- A
Parada de Autobuses de Mezcales
Carretera Vallarta-Tepic # 210 , Colonia Ica, Menchaca, 63150 Tepic, Nay.
Stops in Guadalajara
- ATerminal de Autobuses de Guadalajara, Carretera Libre a Zapotlanejo y entronque carretera a Tonalá Km. 1.5, 44100 Guadalajara
- C
Estación Juárez Parada de Autobuses
Av. Del Federalismo Nte. 800 (esq. Av. Juárez), 44100 Guadalajara, Jalisco, Mexico - DCalle Los Ángeles 218, Las Conchas, 44460 Guadalajara, Jal., Mexico
- E
Parada de Autobuses del Mercado Del Mar en Zapopan
Prolongación Pino Suárez No. 453 (a un costado del Mercado del Mar) - El Vigìa, 45140 Zapopan - F
Santa Alicia
Plaza Santa Alicia, Avenida Guadalupe, Zapopan, Mexico
Compare bus companies
Frequently asked questions about traveling from Mezcales to Guadalajara, MX by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mezcales to Guadalajara?
The cheapest bus tickets from Mezcales to Guadalajara start from $48. The average price for this route is around $49. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mezcales to Guadalajara?
The average bus trip duration from Mezcales to Guadalajara is 4h 18m, covering a distance of 130 miles (209 km). The quickest bus can get you there in 2h 50m and is operated by Primera Plus.
Which bus companies service the Mezcales to Guadalajara route?
Several major bus companies operate on this route with 31 buses available per day, including services from Pacifico, Futura, Primera Plus, Chihuahuenses, Norte de Sonora, Nayar.
What is the earliest and latest departure time for the bus from Mezcales to Guadalajara?
The earliest bus departs from Mezcales to Guadalajara at 12:45am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Mezcales to Guadalajara?
A bus trip from Mezcales to Guadalajara generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mezcales to Guadalajara?
According to Busbud customers, the highest-rated bus company on this route is Futura, with an average rating of 3.4 out of 5 stars based on 735 reviews.
Which bus company has the best Wi-Fi from Mezcales to Guadalajara?
Based on reviews on Busbud, the bus company Chihuahuenses has the best Wi-Fi rating with a score of 1.8.
Which bus company has the most timely service from Mezcales to Guadalajara?
According to Busbud traveller reviews, the most timely bus company on this route is Nayar, with a punctuality rating of 3.1 out of 5 stars.
Which bus company has the cleanest buses from Mezcales to Guadalajara?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Futura, with a cleanliness rating of 3.8 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mezcales to Guadalajara, MX was searched and found on Dec 6, 2025 with a price of $37To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mezcales to Guadalajara, MX, as early as possible.
You can expect to pay from $37 to $51 for a bus ticket from Mezcales to Guadalajara, MX based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-12-06.
Usually Primera Plus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
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