Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Karlsruhe | Lyon - Perrache Bus Station | CheapestFastest | ||||
| Bus | Karlsruhe | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Today at 6:33 AM CET.
Compare 3 ways to go from Karlsruhe to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 5 hours 30 minutes, and with fares starting at just $91, it presents an excellent value for a comfortable ride.
Where are the popular stops in Karlsruhe and Lyon?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Karlsruhe to Lyon by bus
How far is Karlsruhe from Lyon?
Karlsruhe and Lyon are 450 km (279 miles) apart.
What are the departure and arrival locations for buses traveling from Karlsruhe to Lyon?
Buses departing from Südseite Hauptbahnhof in Karlsruhe will take you to Lyon Airport in Lyon.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Lyon was searched and found on Nov 27, 2025 with a price of $35To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Lyon, as early as possible.
You can expect to pay from $35 to $121 for a bus ticket from Karlsruhe to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-11-27.
What's the cheapest way to go from Karlsruhe to Lyon?
The bus is the cheapest travel choice for this destination
