Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Karlsruhe | Lyon - Perrache Bus Station | CheapestFastest | ||||
| Bus | Karlsruhe | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Today at 6:33 AM CET.
Compare 3 ways to travel from Karlsruhe to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 5 hours 30 minutes and with fares starting at just R 1 100, it presents an excellent value for a comfortable ride.
Where are the popular stops in Karlsruhe and Lyon?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Lyon
- A
Lyon Airport
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Karlsruhe to Lyon by bus
How much does a bus ticket from Karlsruhe to Lyon cost?
The bus ticket price from Karlsruhe to Lyon starts at R 448. The best way to find cheap bus tickets from Karlsruhe to Lyon is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Karlsruhe to Lyon?
The average travel time between Karlsruhe and Lyon is around 9h 25m, although the fastest bus will take about 7h 55m. This is the time it takes to travel the 450 km that separates the two cities.
How many daily bus connections are there between Karlsruhe and Lyon?
The number of buses from Karlsruhe to Lyon can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Karlsruhe to Lyon by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Karlsruhe to Lyon?
When taking the bus from Karlsruhe to Lyon, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus.
What are the departure and arrival stations when taking the bus from Karlsruhe to Lyon?
Buses travelling between Karlsruhe and Lyon leave from Südseite Hauptbahnhof or Karlsruhe Hbf and arrive at Lyon Airport, Perrache, Lyon.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Lyon was searched and found on 27 Nov 2025 with a price of R 425To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Lyon as early as possible.
You can expect to pay from R 425 to R 1 467 for a bus ticket from Karlsruhe to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 425, which is on 2025-11-27.
What's the cheapest way to go from Karlsruhe to Lyon?
The bus is the cheapest travel choice for this destination
