Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Karlsruhe | Lyon - Perrache Bus Station | CheapestFastest | ||||
| Bus | Karlsruhe | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Today at 06:33 CET.
Compare 3 ways to travel from Karlsruhe to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 5 hours 30 minutes and with fares starting at just £49, it presents an excellent value for a comfortable ride.
Where are the popular stops in Karlsruhe and Lyon?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling by bus from Karlsruhe to Lyon
What's the distance between Karlsruhe and Lyon by coach?
The journey from Karlsruhe to Lyon by coach covers an approximate distance of 279 miles (450 km).
How can I travel from Karlsruhe to Lyon avoiding air travel?
To travel from Karlsruhe to Lyon without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Lyon was searched and found on 27 Nov 2025 with a price of £19To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Lyon as early as possible.
You can expect to pay from £19 to £65 for a bus ticket from Karlsruhe to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at £19, which is on 2025-11-27.
What's the cheapest way to go from Karlsruhe to Lyon?
The bus is the cheapest travel choice for this destination
