Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Südseite Hauptbahnhof | Lampugnano bus station | CheapestFastest | |||||
| Südseite Hauptbahnhof | Milan (Malpensa Aeroporto Terminal 1) | No tags | |||||
Flixtrain + Flixbus | Karlsruhe Hbf | Milan (Malpensa Aeroporto Terminal 1) | No tags | |||||
 | Karlsruhe | Lampugnano | No tags | |||||
| Südseite Hauptbahnhof | Milan (Malpensa Aeroporto Terminal 1) | No tags |
Last refresh of the prices: Last Tuesday at 13:58 CET.
Compare 3 ways to travel from Karlsruhe to Milano
Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 5 hours 50 minutes and with fares starting at just £34, it presents an excellent value for a comfortable ride.
Where are the popular stops in Karlsruhe and Milano?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- CPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Frequently asked questions about travelling by bus from Karlsruhe to Milano
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Karlsruhe to Milano?
The cheapest coach tickets from Karlsruhe to Milano start from £27. The average price for this route is around £39. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Karlsruhe to Milano?
The average bus journey time from Karlsruhe to Milano is 8h 55m, covering a distance of 244 miles. The fastest bus can take you there in 7h 20m and is operated by FlixBus.
Which bus companies service the Karlsruhe to Milano route?
Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus, BlaBlaCar Bus, MarinoBus.
What is the earliest and latest departure time for the bus from Karlsruhe to Milano?
The earliest bus departs from Karlsruhe to Milano at 00:25. And the latest bus departs at 23:40.
What are the CO₂ emissions for the bus trip from Karlsruhe to Milano?
A bus journey from Karlsruhe to Milano produces an estimated 10 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Karlsruhe to Milano?
According to Busbud customers, the highest-rated bus company on this route is MarinoBus, with an average rating of 4.1 out of 5 stars based on 893 reviews.
Which company has the best Wi-Fi from Karlsruhe to Milano?
Based on Busbud reviews, the bus company MarinoBus has the best Wi-Fi rating with a score of 3.2.
Which bus company offers the most punctual service from Karlsruhe to Milano?
According to Busbud traveller reviews, the most punctual bus company on this route is MarinoBus, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Karlsruhe to Milano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is MarinoBus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Milano was searched and found on 1 Dec 2025 with a price of £25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Milano as early as possible.
You can expect to pay from £25 to £92 for a bus ticket from Karlsruhe to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at £25, which is on 2025-12-01.
