Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Südseite Hauptbahnhof | Lampugnano bus station | CheapestFastest | |||||
| Südseite Hauptbahnhof | Milan (Malpensa Aeroporto Terminal 1) | No tags | |||||
 | Karlsruhe | Lampugnano | No tags | |||||
| Südseite Hauptbahnhof | Aeroporto Malpensa T2 | No tags | |||||
| Südseite Hauptbahnhof | Lampugnano bus station | No tags |
Last refresh of the prices: Today at 6:44 AM CEST.
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Compare 3 ways to go from Karlsruhe to Milano.
Busbud recommends carpooling from Karlsruhe to MilanoAmong the sustainable travel choices, the carpool stands out as the good way to reach Milano. The journey takes about 5 hours 50 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.
Bus Karlsruhe to Milano: Trip Overview
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Karlsruhe to Milano Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Karlsruhe to Milano.
We make sure you can find a bus service from Karlsruhe to Milano from the most reliable bus companies operating this trip.
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Where are the popular stops in Karlsruhe and Milano?
Frequently asked questions for your trip Karlsruhe - Milano
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Milano was searched and found on Sep 24, 2025 with a price of $32To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Milano, as early as possible.
You can expect to pay from $32 to $148 for a bus ticket from Karlsruhe to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-09-24.
Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Karlsruhe to Milano but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Karlsruhe to Milano, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Karlsruhe to Milano will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Karlsruhe to Milano.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
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Popular Buses Connecting Karlsruhe
Buses Leaving from Karlsruhe
- Bus from Karlsruhe to Kaiserslautern
- Bus Karlsruhe - Regensburg
- Karlsruhe - Paris
- Bus from Karlsruhe to Stuttgart
- Bus Karlsruhe - Hamburg
- Karlsruhe - Paderborn
- Bus from Karlsruhe to Freiburg
- Bus Karlsruhe - Frankfurt am Main
- Karlsruhe - Heidelberg
- Bus from Karlsruhe to Ulm
- Bus Karlsruhe - Cologne
- Karlsruhe - Dortmund
- Bus from Karlsruhe to Reutlingen
- Bus Karlsruhe - Munich
- Karlsruhe - Berlin
Buses Going to Karlsruhe
- Bus from Darmstadt to Karlsruhe
- Bus Paderborn - Karlsruhe
- Regensburg - Karlsruhe
- Bus from Mannheim to Karlsruhe
- Bus Cologne - Karlsruhe
- Wertheim - Karlsruhe
- Bus from Frankfurt am Main to Karlsruhe
- Bus Heidelberg - Karlsruhe
- Stuttgart - Karlsruhe
- Bus from Munich to Karlsruhe
- Bus Berlin - Karlsruhe
- Nuremberg - Karlsruhe
- Bus from Rust to Karlsruhe
- Bus Freiburg - Karlsruhe
- Rostock - Karlsruhe
Popular Buses Connecting Milano
Buses Leaving from Milano
- Bus from Milano to Sanremo
- Bus Milano - Bisceglie
- Milano - Monza
- Bus from Milano to Bari
- Bus Milano - Verona
- Milano - Landau
- Bus from Milano to Como
- Bus Milano - Genoa
- Milano - Venice
- Bus from Milano to Florence
- Bus Milano - Breuil-Cervinia
- Milano - Courmayeur
- Bus from Milano to Naples
- Bus Milano - Padova
- Milano - Passo del Tonale
Buses Going to Milano
- Bus from Outlet to Milano
- Bus London - Milano
- Loreto - Milano
- Bus from Bratislava to Milano
- Bus Bologna - Milano
- Amsterdam - Milano
- Bus from Venice to Milano
- Bus Genoa - Milano
- Florence - Milano
- Bus from Como to Milano
- Bus Palermo - Milano
- Naples - Milano
- Bus from Padova to Milano
- Bus Courmayeur - Milano
- Pisa - Milano
Popular routes in this country
- Bus from Frankfurt am Main to Berlin
- Bus Stuttgart - Berlin
- Berlin - Dresden
- Bus from Cologne to Berlin
- Bus Munich - Berlin
- Berlin - Leipzig
- Bus from Dresden to Berlin
- Bus Cologne - Hamburg
- Leipzig - Berlin
- Bus from Düsseldorf to Berlin
- Bus Hanover - Berlin
- Berlin - Stuttgart
- Bus from Stuttgart to Frankfurt am Main
- Bus Hamburg - Cologne
- Düsseldorf - Hamburg