Bus Tickets from Karlsruhe to Madrid

Previously seen trips

Next departures for Karlsruhe to Madrid on November 25
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Südseite Hauptbahnhof
Madrid (South)No tags
FlixBusBus
Südseite Hauptbahnhof
Madrid (South)No tags
FlixBusBus
Südseite Hauptbahnhof
Madrid (South)No tags
FlixBusBus
Südseite Hauptbahnhof
Madrid (South)No tags
FlixBusBus
Südseite Hauptbahnhof
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags

Compare 2 ways to go from Karlsruhe to Madrid

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Madrid. The journey takes about 1 day, 3 hours 35 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.

3bus per day
1d 3hAverage Duration
836 milesDistance
34kgCO₂ emissions
Average Price$76 - $311Average Duration1d 3h
34kg CO₂e
Carpool
Average Price$166 - $166Average Duration18h 50m
57kg CO₂e

Frequently asked questions about traveling from Karlsruhe to Madrid by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/23
$95
11/24
$93
Today
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11/26
No data
11/27
No data
11/28
No data
11/29
No data
11/30
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busbud logoThe cheapest trip from Karlsruhe to Madrid was searched and found on Nov 24, 2025 with a price of $93

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Madrid, as early as possible.

What's the cheapest way to go from Karlsruhe to Madrid?

busbud logoThe bus is the cheapest travel choice for this destination

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