Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Karlsruhe | Frankfurt - Main bus station | Cheapest | |||||
 | Südseite Hauptbahnhof | FRA Frankfurt airport | Fastest | |||||
| Karlsruhe | Frankfurt - Main bus station | No tags | |||||
| Südseite Hauptbahnhof | FRA Frankfurt airport | No tags | |||||
| Karlsruhe | Frankfurt - Main bus station | No tags |
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Compare 3 ways to go from Karlsruhe to Frankfurt am Main.
Busbud recommends carpooling from Karlsruhe to Frankfurt am MainAmong the sustainable travel choices, the carpool stands out as the good way to reach Frankfurt am Main. The journey takes about 1 hour 30 minutes and with fares starting at just $9, it presents an excellent value for a comfortable ride.
Bus Karlsruhe to Frankfurt am Main: Trip Overview
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Karlsruhe to Frankfurt am Main Bus
Busbud helps you find a bus from Karlsruhe to Frankfurt am Main. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Karlsruhe to Frankfurt am Main will be provided by the most trusted bus companies.
Discover how much the bus trip from Karlsruhe to Frankfurt am Main will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Karlsruhe and Frankfurt am Main?
Frequently asked questions for your trip Karlsruhe - Frankfurt am Main
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Frankfurt am Main was searched and found on Sep 12, 2025 with a price of $8To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Frankfurt am Main, as early as possible.
You can expect to pay from $8 to $17 for a bus ticket from Karlsruhe to Frankfurt am Main based on the last 2 days. You can expect to find the cheapest price for the trip at $8 which is on 2025-09-16.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Karlsruhe and Frankfurt am Main!
Much more than a mere vehicle taking you from Karlsruhe to Frankfurt am Main, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Karlsruhe to Frankfurt am Main will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Karlsruhe to Frankfurt am Main.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Popular Buses Connecting Karlsruhe
Buses Leaving from Karlsruhe
- Bus from Karlsruhe to Kaiserslautern
- Bus Karlsruhe - Regensburg
- Karlsruhe - Paris
- Bus from Karlsruhe to Hamburg
- Bus Karlsruhe - Stuttgart
- Karlsruhe - Paderborn
- Bus from Karlsruhe to Heidelberg
- Bus Karlsruhe - Freiburg
- Karlsruhe - Frankfurt am Main
- Bus from Karlsruhe to Ulm
- Bus Karlsruhe - Cologne
- Karlsruhe - Dortmund
- Bus from Karlsruhe to Reutlingen
- Bus Karlsruhe - Berlin
- Karlsruhe - Munich
Buses Going to Karlsruhe
- Bus from Darmstadt to Karlsruhe
- Bus Paderborn - Karlsruhe
- Regensburg - Karlsruhe
- Bus from Mannheim to Karlsruhe
- Bus Cologne - Karlsruhe
- Berlin - Karlsruhe
- Bus from Heidelberg to Karlsruhe
- Bus Stuttgart - Karlsruhe
- Frankfurt am Main - Karlsruhe
- Bus from Munich to Karlsruhe
- Bus Nuremberg - Karlsruhe
- Rust - Karlsruhe
- Bus from Rosenheim to Karlsruhe
- Bus Kassel - Karlsruhe
- Wertheim - Karlsruhe
Popular Buses Connecting Frankfurt am Main
Buses Leaving from Frankfurt am Main
- Bus from Frankfurt am Main to London
- Bus Frankfurt am Main - Pristina
- Frankfurt am Main - Essen
- Bus from Frankfurt am Main to Amsterdam
- Bus Frankfurt am Main - Luxembourg
- Frankfurt am Main - Rust
- Bus from Frankfurt am Main to Hahn
- Bus Frankfurt am Main - Munich
- Frankfurt am Main - Eisenach
- Bus from Frankfurt am Main to Mainz
- Bus Frankfurt am Main - Stuttgart
- Frankfurt am Main - Heidelberg
- Bus from Frankfurt am Main to Düsseldorf
- Bus Frankfurt am Main - Hamburg
- Frankfurt am Main - Hanover
Buses Going to Frankfurt am Main
- Bus from Munich to Frankfurt am Main
- Bus Paris - Frankfurt am Main
- Tours - Frankfurt am Main
- Bus from Strasbourg to Frankfurt am Main
- Bus Heidelberg - Frankfurt am Main
- Heathrow - Frankfurt am Main
- Bus from Hahn to Frankfurt am Main
- Bus Cologne - Frankfurt am Main
- Düsseldorf - Frankfurt am Main
- Bus from Nuremberg to Frankfurt am Main
- Bus Bonn - Frankfurt am Main
- Dortmund - Frankfurt am Main
- Bus from Koblenz to Frankfurt am Main
- Bus Karlsruhe - Frankfurt am Main
- Kaiserslautern - Frankfurt am Main
Popular routes in this country
- Bus from Frankfurt am Main to Berlin
- Bus Berlin - Dresden
- Stuttgart - Berlin
- Bus from Cologne to Berlin
- Bus Munich - Berlin
- Berlin - Leipzig
- Bus from Dresden to Berlin
- Bus Cologne - Hamburg
- Leipzig - Berlin
- Bus from Düsseldorf to Berlin
- Bus Hanover - Berlin
- Berlin - Stuttgart
- Bus from Stuttgart to Frankfurt am Main
- Bus Frankfurt am Main - Cologne
- Hamburg - Cologne