Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Karlsruhe | Lyon - Perrache Bus Station | CheapestFastest | ||||
| Bus | Karlsruhe | Lyon - Perrache Bus Station | No tags |
Last refresh of the prices: Today at 6:33 AM CET.
Compare 3 ways to go from Karlsruhe to Lyon
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Lyon. The journey takes about 5 hours 30 minutes and with fares starting at just $63, it presents an excellent value for a comfortable ride.
1carpool per day
5h 30mAverage Duration
279 milesDistance
19kgCO₂ emissions
Where are the popular stops in Karlsruhe and Lyon?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
3.5 out of 5 stars3.5/511,447 reviews
3.5 out of 5 stars3.5/511,161 reviews
FR bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from Karlsruhe to Lyon by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/24
No data
11/25
No data
Today
$48
11/27
$25
11/28
$29
11/29
$27
11/30
$29
12/01
No data
The cheapest trip from Karlsruhe to Lyon was searched and found on Nov 27, 2025 with a price of $25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Lyon, as early as possible.
You can expect to pay from $25 to $84 for a bus ticket from Karlsruhe to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-11-27.
What's the cheapest way to go from Karlsruhe to Lyon?
The bus is the cheapest travel choice for this destination
