How far is Wilmington from Florence?

The distance between the two cities is 443 miles (714 km).

What are the departure and arrival stations when taking the bus from Wilmington to Florence?

Most of the buses traveling from Wilmington to Florence leave from Wilmington Bus Station and arrive at Florence Bus Station. These are the primary departure and arrival locations on this route, but you can also find other options that could better fit your plans.

What are the best sights and things to do in Florence?

Once in Florence, you can start exploring the city and discover its surroundings. The top sights and things to do are Basilica di San Lorenzo, Palazzo Vecchio, Basilica Santa Croce, Santa Maria Novella and Galleria dell’Accademia.

Bus Wilmington to Florence from $84 | Compare & Save up to 37%

TodayJul 25

TomorrowJul 26

SunJul 27

MonJul 28

from $71

TueJul 29

WedJul 30

ThuJul 31

FriAug 1

Cheap buses leaving Monday

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: July 28 at 9:25pm
Departure city: Wilmington
Departure location: Wilmington Bus Station
Arrival time: July 29 at 12:45pm
Destination city: Florence
Destination location: Bus station
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 15h 20m
This trip is recommended because it is: Fastest
Departure time: July 28 at 4:50pm
Departure city: Wilmington
Departure location: Newark (DE)
Arrival time: July 29 at 5:45am
Destination city: Florence
Destination location: Florence, SC
Operated by: FlixBus
Vehicle: BusDuration: 12h 55m
Departure time: July 28 at 1:50pm
Departure city: Wilmington
Departure location: Wilmington Bus Station
Arrival time: July 29 at 5:45am
Destination city: Florence
Destination location: Florence, SC
Operated by: Greyhound Lines, Inc. + FlixBus
Greyhound Lines, Inc. + FlixBus
Vehicle: BusDuration: 15h 55m
Departure time: July 28 at 4:50pm
Departure city: Wilmington
Departure location: Newark (DE)
Arrival time: July 29 at 5:45am
Destination city: Florence
Destination location: Florence, SC
Operated by: FlixBus
Vehicle: BusDuration: 12h 55m
Departure time: July 28 at 7:30pm
Departure city: Wilmington
Departure location: Newark (DE)
Arrival time: July 29 at 12:45pm
Destination city: Florence
Destination location: Bus station
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 17h 15m

Accepted payments

Compare 2 ways to go from Wilmington to Florence.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$45 - $174	Average Duration15h 40m	CO₂ emissions 18kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$141 - $312	Average Duration10h 1m	CO₂ emissions 66kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Wilmington to Florence

Among the sustainable travel choices, the train stands out as the good way to reach Florence. The journey takes about 10 hours 1 minute and with fares starting at just $141, it presents an excellent value for a comfortable ride.

2train per day

10h 1mAverage Duration

$141Cheapest ticket

66kgCO₂ emissions

Bus Wilmington, DE to Florence, SC, US: Trip Overview

Average ticket price$99

Average bus trip duration15h 40m

Number of daily buses2

Earliest bus departure11:20am

Distance438 miles (705 km)

Latest bus departure9:25pm

Compare bus companies

FlixBus

3.5/59,723 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,133 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Wilmington to Florence Bus

Busbud helps you find a bus from Wilmington to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Wilmington to Florence will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Wilmington to Florence, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in Wilmington and Florence?

Stops in Wilmington

A - Wilmington Bus Station

B - Wilmington Station

C - Wilmington Bus Stop

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions for your trip Wilmington, DE - Florence, SC, US

How far is Wilmington from Florence?
What are the departure and arrival stations when taking the bus from Wilmington to Florence?
What are the best sights and things to do in Florence?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

07/23

No data

07/24

No data

Today

$84

07/26

No data

07/27

No data

07/28

$96

07/29

No data

07/30

$116

The cheapest trip from Wilmington, DE to Florence, SC, US was searched and found on Jul 25, 2025 with a price of $84

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Florence, SC, US, as early as possible.

You can expect to pay from $84 to $116 for a bus ticket from Wilmington, DE to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $96 which is on 2025-07-28.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Florence!

Much more than a mere vehicle taking you from Wilmington to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wilmington to Florence that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Wilmington, DE to Florence, SC, US?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time15h 40m	Avg Price$99	Daily Departures2
Vehicle TypeTrain	Travel Time10h 1m	Avg Price$141	Daily Departures2

Will you be returning to Wilmington, DE by bus?

Bus from Wilmington, DE to Florence, SC, US

You can also go to Florence, SC, US by train

Train from Wilmington, DE to Florence, SC, US

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Wilmington, DE to Florence, SC, US

Cheap buses leaving Monday

One passenger / one way

Compare 2 ways to go from Wilmington to Florence.

Bus Wilmington, DE to Florence, SC, US: Trip Overview

Compare bus companies

Wilmington to Florence Bus

Where are the popular stops in Wilmington and Florence?

Frequently asked questions for your trip Wilmington, DE - Florence, SC, US

How far is Wilmington from Florence?

What are the departure and arrival stations when taking the bus from Wilmington to Florence?

What are the best sights and things to do in Florence?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Wilmington, DE to Florence, SC, US?

Will you be returning to Wilmington, DE by bus?

You can also go to Florence, SC, US by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Wilmington

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Popular Buses Connecting Florence

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Buses Going to Florence

Popular routes in this country

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