Bus from Florence, SC, US to Boston, MA, US: Tickets & Schedules

Next bus departures

Next departures for Florence to Boston on January 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
151 Steel Pl, CambridgeCheapest
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
Boston (South Station)Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Bus station
BrooklineNo tags

Last refresh of the prices: Last Friday at 11:01 AM EST.

Compare 2 ways to go from Florence to Boston

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach Boston. The journey takes about 1 day, 2 hours 50 minutes and with fares starting at just $90, it presents an excellent value for a comfortable ride.

4bus per day
1d 2hAverage Duration
733 milesDistance
30kgCO₂ emissions
Average Price$90 - $349Average Duration1d 2h
30kg CO₂e
Average Price$138 - $1,858Average Duration20h 24m
106kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Boston, MA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Florence to Boston?

    The cheapest bus tickets from Florence to Boston start from $90. The average price for this route is around $202. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Florence to Boston?

    The average bus trip duration from Florence to Boston is 1d 2h, covering a distance of 733 miles (1182 km). The quickest bus can get you there in 21h 40m and is operated by FlixBus.

  3. Which bus companies service the Florence to Boston route?

    Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Florence to Boston?

    The earliest bus departs from Florence to Boston at 12:05am. And the latest bus departs at 4:30pm.

  5. What are the CO₂ emissions for the bus trip from Florence to Boston?

    A bus trip from Florence to Boston generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Florence to Boston?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12050 reviews.

  7. Which bus company has the best Wi-Fi from Florence to Boston?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Florence to Boston?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Florence to Boston?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/16
$147
01/17
$148
Today
$129
01/19
No data
01/20
No data
01/21
No data
01/22
$95
01/23
$111
busbud logoThe cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Jan 22, 2026 with a price of $95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.

You can expect to pay from $95 to $148 for a bus ticket from Florence, SC, US to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $95 which is on 2026-01-22.

What's the cheapest way to go from Florence, SC, US to Boston, MA, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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