Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Bus station | 151 Steel Pl, Cambridge | No tags | ||||
 | Bus | Bus station | Boston (South Station) | No tags | ||||
Greyhound + FlixBus | Bus | Bus station | 151 Steel Pl, Cambridge | No tags | ||||
| Bus | Bus station | Boston (South Station) | No tags | ||||
| Bus | Bus station | Boston (South Station) | No tags |
Compare 2 ways to go from Florence to Boston
Among the sustainable travel choices, the train stands out as a good way to reach Boston. The journey takes about 20 hours 32 minutes, and with fares starting at just $171, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and Boston?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Frequently asked questions about travelling from Florence, SC, US to Boston, MA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Boston?
The cheapest bus tickets from Florence to Boston start from $143. The average price for this route is around $212. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Boston?
The average bus travel time from Florence to Boston is 1d 2h, covering a distance of 1182 km. The quickest bus can get you there in 22h 5m and is operated by Greyhound.
Which bus companies service the Florence to Boston route?
What are the earliest and latest departure times for the bus from Florence to Boston?
The earliest bus departs from Florence to Boston at 12:05am. And the latest bus departs at 4:30pm.
What are the CO₂ emissions for the bus trip from Florence to Boston?
A bus trip from Florence to Boston generates an estimated 30 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Florence to Boston?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Florence to Boston?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Florence to Boston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Boston, MA, US was searched and found on Dec 8, 2025 with a price of $216To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Boston, MA, US, as early as possible.
What's the cheapest way to go from Florence, SC, US to Boston, MA, US?
The bus is the cheapest travel choice for this destination
