Bus from Wilmington, DE to Florence, SC, US: Tickets & Timetables

Previously seen journeys

Next departures from Wilmington to Florence on 26 March
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Bus
Wilmington Bus Station
Florence, SCNo tags
Greyhound + FlixBus
Bus
Wilmington Bus Station
Florence, SCNo tags
Greyhound + FlixBus
Bus
Wilmington Bus Station
Florence, SCNo tags
Greyhound + FlixBus
Bus
Wilmington Bus Station
Bus stationNo tags
Greyhound + FlixBus
Bus
Wilmington Bus Station
Florence, SCNo tags

Compare 2 ways to travel from Wilmington to Florence

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Florence. The journey takes about 11 hours 11 minutes and with fares starting at just R 1 582, it presents an excellent value for a comfortable ride.

3train per day
11h 11mAverage duration
721 kmDistance
66kgCO₂ emissions
Average priceR 1 125 - R 3 842Average duration18h 25m
18kg CO₂e
Average priceR 1 582 - R 8 259Average duration11h 11m
66kg CO₂e

Frequently asked questions about travelling from Wilmington, DE to Florence, SC, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Wilmington to Florence?

    The cheapest bus tickets from Wilmington to Florence start at R 1 125. The average price for this route is around R 1 879. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Wilmington to Florence?

    The average bus journey time from Wilmington to Florence is 18h 25m, covering a distance of 709 km. The fastest bus gets you there in 12h 55m and is operated by FlixBus.

  3. Which bus companies service the Wilmington to Florence route?

    Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Wilmington to Florence?

    The earliest bus departs from Wilmington to Florence at 11:20. And the latest bus departs at 21:25.

  5. What are the CO₂ emissions for the bus trip from Wilmington to Florence?

    A bus trip from Wilmington to Florence produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Wilmington to Florence?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 12330 reviews.

  7. Which bus company has the best Wi-Fi from Wilmington to Florence?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Wilmington to Florence?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Wilmington to Florence?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/03
No data
25/03
R 1 648
Today
No data
27/03
No data
28/03
No data
29/03
No data
30/03
No data
31/03
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busbud logoThe cheapest trip from Wilmington, DE to Florence, SC, US was searched and found on 25 Mar 2026 with a price of R 1 648

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Florence, SC, US as early as possible.

What's the cheapest way to go from Wilmington, DE to Florence, SC, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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