Compare 2 ways to go from Saint Paul to La Crosse.
Busbud recommends taking the train from Saint Paul to La CrosseAmong the sustainable travel choices, the train stands out as the good way to reach La Crosse. The journey takes about 2 hours 38 minutes and with fares starting at just $20, it presents an excellent value for a comfortable ride.
Bus Saint Paul, US to La Crosse, WI: Trip Overview
Compare bus companies
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Saint Paul to La Crosse Bus
With Busbud, comparing and booking tickets for a bus from Saint Paul to La Crosse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Saint Paul to La Crosse from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses traveling from Saint Paul to La Crosse, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Saint Paul, US - La Crosse, WI
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Saint Paul, US to La Crosse, WI was searched and found on Aug 9, 2025 with a price of $29To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Saint Paul, US to La Crosse, WI, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Saint Paul to La Crosse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Saint Paul to La Crosse, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Saint Paul to La Crosse that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Saint Paul to La Crosse.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Saint Paul
Buses Leaving from Saint Paul
Buses Going to Saint Paul
Popular Buses Connecting La Crosse
Buses Leaving from La Crosse
- Bus from La Crosse to Madison
- Bus La Crosse - Minneapolis
- La Crosse - Milwaukee
- Bus from La Crosse to Winona
- Bus La Crosse - Oshkosh
- La Crosse - Green Bay
- Bus from La Crosse to Janesville
- Bus La Crosse - Appleton
- La Crosse - Rochester
- Bus from La Crosse to Rockford
- Bus La Crosse - Maple Grove
- La Crosse - Ames
- Bus from La Crosse to Mankato