How far is Rome from Syracuse?

The distance separating Rome and Syracuse is 365 miles (588 km).

What are the departure and arrival stations when taking the bus from Rome to Syracuse?

Most of the buses traveling from Rome to Syracuse leave from Rome Tiburtina Bus Station and arrive at Fermata dell'autobus Siracusa. These are the most popular pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Onondaga Lake Park, Central New York Playhouse, Rosamond Gifford Zoo, Oncenter War Memorial Arena and Erie Canal Museum.

Bus Rome to Syracuse from $44 | Refundable Tickets

Next bus departures

Next departures for Rome to Syracuse on November 13
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:40pm	Aeroporto Ciampino Airport (CIA)	22h	8:40pm	Terminal Interbus	Cheapest
Bus	8:10pm	Rome Tiburtina Bus Station	13h 25m	9:35am	Terminal Interbus	Fastest
Bus	10:35pm	Rome Fiumicino Airport	22h 5m	8:40pm	Terminal Interbus	No tags

Last refresh of the prices: Today at 4:15 PM CET.

Compare 3 ways to go from Rome to Syracuse

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Syracuse. The journey takes about 9 hours 30 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.

2carpool per day

9h 30mAverage Duration

365 milesDistance

25kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$37 - $152	Average Duration19h 25m	CO₂ emissions 15kg CO₂e
Train	Average Price$58 - $138	Average Duration11h 2m	CO₂ emissions 14kg CO₂e
Carpool	Average Price$44 - $88	Average Duration9h 30m	CO₂ emissions 25kg CO₂e

Compare bus companies

FlixBus

3.5/511,290 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

FlixBus

3.5/511,290 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Where are the popular stops in Rome and Syracuse?

Stops in Rome

A - Rome Tiburtina Bus Station

B - Rome Ciampino Airport

C - Rome Fiumicino Airport

D - Castro Pretorio

E - Roma

F - Anagnina

Stops in Syracuse

A - Fermata dell'autobus Siracusa

B - Siracusa

C - Siracusa - Terminal Bus (Stazione FS)

Frequently asked questions about traveling from Rome to Syracuse by bus

How far is Rome from Syracuse?
What are the departure and arrival stations when taking the bus from Rome to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/10

$111

11/11

$89

Today

$51

11/13

$84

11/14

$59

11/15

$46

11/16

$70

11/17

$58

The cheapest trip from Rome to Syracuse was searched and found on Nov 15, 2025 with a price of $46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Syracuse, as early as possible.

You can expect to pay from $46 to $124 for a bus ticket from Rome to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2025-11-15.