Find coaches from Rome to Syracuse

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Today8 Aug
from US$123
Tomorrow9 Aug
from US$123
Sun10 Aug
Mon11 Aug
from US$113
Tue12 Aug
Wed13 Aug
Thu14 Aug
Fri15 Aug

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 9 August at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 10 August at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Rome
    Departure location: Rome Fiumicino Airport
    Arrival time: 10 August at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 9 August at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 9 August at
    Departure city: Rome
    Departure location: Aeroporto Ciampino Airport (CIA)
    Arrival time: 10 August at
    Destination city: Syracuse
    Destination location: Terminal Interbus
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Accepted payments

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Compare 3 ways to travel from Rome to Syracuse

Bus
Average priceUS$52 - US$189Average duration19h 25m
15kg CO₂e5 out of 5 stars
Train
Average priceUS$60 - US$139Average duration11h 2m
14kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average priceUS$44 - US$88Average duration9h 30m
25kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Rome to Syracuse

Among the sustainable travel choices, the carpool stands out as a good way to reach Syracuse. The journey takes about 9 hours 30 minutes and with fares starting at just US$44, it presents an excellent value for a comfortable ride.

2carpool per day
9h 30mAverage duration
US$44Cheapest ticket
25kgCO₂ emissions

Bus Rome to Syracuse: Trip Overview

Average ticket priceUS$114
Average bus trip duration19h 25m
Number of daily buses3
Earliest bus departure01:15
Distance365 miles
Latest bus departure23:55

Rome to Syracuse Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rome to Syracuse.

Bus service from Rome to Syracuse will be provided by the most trusted bus companies.

Discover how much the bus trip from Rome to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Rome - Syracuse

  1. What's the distance between Rome and Syracuse by coach?

    The distance between Rome and Syracuse by coach is approximately 365 miles (588 km).

  2. How can I travel from Rome to Syracuse avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/08
US$121
07/08
US$122
Today
US$119
09/08
US$118
10/08
US$105
11/08
US$109
12/08
US$88
13/08
US$87
busbud logoThe cheapest trip from Rome to Syracuse was searched and found on 13 Aug 2025 with a price of US$87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Syracuse as early as possible.

You can expect to pay from US$87 to US$179 for a bus ticket from Rome to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$87, which is on 2025-08-13.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rome to Syracuse but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Rome to Syracuse, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Rome to Syracuse will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from Rome to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Rome by bus?

Bus from Rome to Syracuse

You can also go to Syracuse by train

Train from Rome to Syracuse

Why choose Busbud?

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