Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 10 hours 50 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 916 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $39
According to 17 reviews, Autoservizi Salemi received a 4.7-star rating for this journey. Travelers were especially satisfied with the staff and the timeliness, but some complained about the wifi. Autoservizi Salemi ticket prices on this trip start at $75
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
With Busbud, comparing and booking tickets for a bus from Rome to Palermo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
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Frequently asked questions for your trip Rome - Palermo
What is the distance between Rome and Palermo?
About 265 miles (428 km) separate Rome and Palermo.
What are the departure and arrival stations when taking the bus from Rome to Palermo?
If you're headed to Palermo from Rome, chances are that your bus will leave from Rome Tiburtina Bus Station and arrive at Terminal Bus Palermo. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Palermo?
Once in Palermo, you can start exploring the city and discover its surroundings. The top sights and things to do are Torre di San Nicolò all'Albergheria, Museo Archeologico Regionale " Antonino Salinas" Galleria Regionale della Sicilia, Orto Botanico and Castello della Zisa.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
08/21
$52
08/22
$131
Today
$25
08/24
$25
08/25
$25
08/26
$25
08/27
$24
08/28
$25
The cheapest trip from Rome to Palermo was searched and found on Aug 27, 2025 with a price of $24
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Palermo, as early as possible.
You can expect to pay from $24 to $166 for a bus ticket from Rome to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $24 which is on 2025-08-27.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Rome to Palermo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rome to Palermo, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Rome to Palermo will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Rome to Palermo, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.