What is the distance between Syracuse and Palermo?

The distance between the two cities is 128 miles (206 km).

What are the departure and arrival stations when taking the bus from Syracuse to Palermo?

If you're headed to Palermo from Syracuse, chances are that your bus will depart from Fermata dell'autobus Siracusa and arrive at Terminal Bus Palermo. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.

What are the best sights and things to do in Palermo?

Once in Palermo, you can start exploring the city and discover its surroundings. The top sights and things to do are Santa Caterina d'Alessandria, Museo Archeologico Regionale " Antonino Salinas" Majolica Museum " Stanze al Genio" Cappella Palatina and Quattro Canti.

Bus Syracuse to Palermo from $17 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Palermo on November 16
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:00am	Syracuse bus station	3h 20m	11:20am	Terminal Bus Palermo	Cheapest
Bus	11:00am	Syracuse bus station	3h 10m	2:10pm	Palermo Oreto Orsi	Fastest
Bus	11:00am	Syracuse bus station	3h 15m	2:15pm	Terminal Bus Palermo	No tags
Bus	7:15am	Terminal Interbus	7h 10m	2:25pm	Terminal Bus Palermo	No tags
Bus	2:00pm	Syracuse bus station	3h 20m	5:20pm	Terminal Bus Palermo	No tags

Next departures for Syracuse to Palermo on November 17
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:00am	Syracuse bus station	3h 15m	11:15am	Terminal Bus Palermo	Cheapest
Bus	8:00am	Syracuse bus station	3h 10m	11:10am	Palermo Oreto Orsi	Fastest
Bus	11:00am	Syracuse bus station	3h 15m	2:15pm	Terminal Bus Palermo	No tags
Bus	7:15am	Terminal Interbus	7h 10m	2:25pm	Terminal Bus Palermo	No tags
Bus	2:00pm	Syracuse bus station	3h 15m	5:15pm	Terminal Bus Palermo	No tags

Next departures for Syracuse to Palermo on November 19
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:00am	Syracuse bus station	3h 15m	11:15am	Terminal Bus Palermo	Cheapest
Bus	8:00am	Syracuse bus station	3h 10m	11:10am	Palermo Oreto Orsi	Fastest
Bus	11:00am	Syracuse bus station	3h 15m	2:15pm	Terminal Bus Palermo	No tags
Bus	7:15am	Terminal Interbus	7h 10m	2:25pm	Terminal Bus Palermo	No tags
Bus	2:00pm	Syracuse bus station	3h 15m	5:15pm	Terminal Bus Palermo	No tags

Next departures for Syracuse to Palermo on November 20
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:00am	Syracuse bus station	3h 15m	11:15am	Terminal Bus Palermo	Cheapest
Bus	8:00am	Syracuse bus station	3h 10m	11:10am	Palermo Oreto Orsi	Fastest
Bus	11:00am	Syracuse bus station	3h 15m	2:15pm	Terminal Bus Palermo	No tags
Bus	7:15am	Terminal Interbus	9h 40m	4:55pm	Terminal Bus Palermo	No tags
Bus	2:00pm	Syracuse bus station	3h 15m	5:15pm	Terminal Bus Palermo	No tags

Next departures for Syracuse to Palermo on November 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	8:00am	Syracuse bus station	3h 15m	11:15am	Terminal Bus Palermo	Cheapest
Bus	8:00am	Syracuse bus station	3h 10m	11:10am	Palermo Oreto Orsi	Fastest
Bus	11:00am	Syracuse bus station	3h 15m	2:15pm	Terminal Bus Palermo	No tags
Bus	7:15am	Terminal Interbus	9h 40m	4:55pm	Terminal Bus Palermo	No tags
Bus	2:00pm	Syracuse bus station	3h 15m	5:15pm	Terminal Bus Palermo	No tags

Last refresh of the prices: Yesterday at 1:05 PM CET.

Compare 3 ways to go from Syracuse to Palermo

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 3 hours 10 minutes and with fares starting at just $15, it presents an excellent value for a comfortable ride.

1carpool per day

3h 10mAverage Duration

128 milesDistance

9kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$21 - $56	Average Duration3h 15m	CO₂ emissions 5kg CO₂e
Train	Average Price$35 - $90	Average Duration6h 34m	CO₂ emissions 5kg CO₂e
Carpool	Average Price$15 - $23	Average Duration3h 10m	CO₂ emissions 9kg CO₂e

Compare bus companies

Interbus Italy

4/5593 reviews

Staff4.3

Timeliness3.8

Cleanliness4.5

Wifi2.3

Users have shared positive experiences, highlighting the punctuality and professionalism of drivers. The trips were smooth with convenient stops for refreshments. However, some noted discrepancies in ticket instructions regarding paper copies and mentioned a lack of onboard amenities like Wi-Fi or toilets despite being advertised. Overall, the service is appreciated for its efficiency and comfort during travel.

Interbus Syracuse Palermo recent customer reviews

The bus was well on time, and it was a pleasant trip. No toilet on the bus, but a stop at a gas station where there was also time to get a snack or drink, so all good.

Feyona V.

October 1, 2025

The online ticket said a paper copy must be produced to the driver. This caused much concern as travelling we did not have a printer access. In fact the driver just scans the QR code on your phone, even though the ticket states this is not acceptable when it is.

Russell G.

May 9, 2025

On time, the driver was helpful with a couple of our questions We are from Australia Comfortable

Lynelle B.

June 1, 2024

FlixBus

3.5/511,326 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Where are the popular stops in Syracuse and Palermo?

Stops in Syracuse

A - Fermata dell'autobus Siracusa

B - Siracusa

C - Siracusa - Terminal Bus (Stazione FS)

Stops in Palermo

A - Terminal Bus Palermo

B - Palermo Airport

C - Piazza Cairoli

D - Fiera

E - Via Paolo Balsamo, 21

F - Via Paolo Balsamo, 31

Frequently asked questions about traveling from Syracuse to Palermo by bus

What is the distance between Syracuse and Palermo?
What are the departure and arrival stations when taking the bus from Syracuse to Palermo?
What are the best sights and things to do in Palermo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/14

$19

11/15

$19

Today

$19

11/17

$19

11/18

$17

11/19

$19

11/20

$19

11/21

$19

The cheapest trip from Syracuse to Palermo was searched and found on Nov 18, 2025 with a price of $17

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Palermo, as early as possible.

You can expect to pay from $17 to $39 for a bus ticket from Syracuse to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2025-11-18.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Syracuse to Palermo?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time3h 15m	Avg Price$21	Daily Departures7
Vehicle TypeTrain	Travel Time6h 34m	Avg Price$36	Daily Departures1
Vehicle TypeCarpool	Travel Time3h 10m	Avg Price$21	Daily Departures1