Next departures for Syracuse to Palermo on November 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse bus station
Terminal Bus Palermo
Cheapest
Bus
Syracuse bus station
Palermo Oreto Orsi
Fastest
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Bus
Terminal Interbus
Terminal Bus Palermo
No tags
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Next departures for Syracuse to Palermo on November 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse bus station
Terminal Bus Palermo
Cheapest
Bus
Syracuse bus station
Palermo Oreto Orsi
Fastest
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Bus
Terminal Interbus
Terminal Bus Palermo
No tags
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Next departures for Syracuse to Palermo on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse bus station
Terminal Bus Palermo
Cheapest
Bus
Syracuse bus station
Palermo Oreto Orsi
Fastest
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Bus
Terminal Interbus
Terminal Bus Palermo
No tags
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Next departures for Syracuse to Palermo on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse bus station
Terminal Bus Palermo
Cheapest
Bus
Syracuse bus station
Palermo Oreto Orsi
Fastest
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Bus
Terminal Interbus
Terminal Bus Palermo
No tags
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Next departures for Syracuse to Palermo on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Syracuse bus station
Terminal Bus Palermo
Cheapest
Bus
Syracuse bus station
Palermo Oreto Orsi
Fastest
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Bus
Terminal Interbus
Terminal Bus Palermo
No tags
Bus
Syracuse bus station
Terminal Bus Palermo
No tags
Last refresh of the prices: Yesterday at 1:05 PM CET.
Compare 3 ways to go from Syracuse to Palermo
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 3 hours 10 minutes and with fares starting at just $15, it presents an excellent value for a comfortable ride.
Users have shared positive experiences, highlighting the punctuality and professionalism of drivers. The trips were smooth with convenient stops for refreshments. However, some noted discrepancies in ticket instructions regarding paper copies and mentioned a lack of onboard amenities like Wi-Fi or toilets despite being advertised. Overall, the service is appreciated for its efficiency and comfort during travel.
Interbus Syracuse Palermo recent customer reviews
The bus was well on time, and it was a pleasant trip. No toilet on the bus, but a stop at a gas station where there was also time to get a snack or drink, so all good.
5 out of 5 stars
Feyona V.
The online ticket said a paper copy must be produced to the driver. This caused much concern as travelling we did not have a printer access. In fact the driver just scans the QR code on your phone, even though the ticket states this is not acceptable when it is.
4 out of 5 stars
Russell G.
On time, the driver was helpful with a couple of our questions
We are from Australia
Comfortable
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Syracuse to Palermo by bus
What is the distance between Syracuse and Palermo?
The distance between the two cities is 128 miles (206 km).
What are the departure and arrival stations when taking the bus from Syracuse to Palermo?
If you're headed to Palermo from Syracuse, chances are that your bus will depart from Fermata dell'autobus Siracusa and arrive at Terminal Bus Palermo. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Palermo?
Once in Palermo, you can start exploring the city and discover its surroundings. The top sights and things to do are Santa Caterina d'Alessandria, Museo Archeologico Regionale " Antonino Salinas" Majolica Museum " Stanze al Genio" Cappella Palatina and Quattro Canti.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/14
$19
11/15
$19
Today
$19
11/17
$19
11/18
$17
11/19
$19
11/20
$19
11/21
$19
The cheapest trip from Syracuse to Palermo was searched and found on Nov 18, 2025 with a price of $17
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Palermo, as early as possible.
You can expect to pay from $17 to $39 for a bus ticket from Syracuse to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2025-11-18.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Syracuse to Palermo?
The bus is the cheapest travel choice for this destination