Next departures for Palermo to Rome on November 14
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Tiburtina
CheapestFastest
Bus
Terminal Bus Palermo
Aeroporto Ciampino Airport (CIA)
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Next departures for Palermo to Rome on November 15
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
Cheapest
Bus
Terminal Bus Palermo
Tiburtina
Fastest
Bus
Terminal Bus Palermo
Aeroporto Ciampino Airport (CIA)
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Next departures for Palermo to Rome on November 16
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
Cheapest
Bus
Terminal Bus Palermo
Tiburtina
Fastest
Bus
Terminal Bus Palermo
Aeroporto Ciampino Airport (CIA)
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Next departures for Palermo to Rome on November 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Tiburtina
CheapestFastest
Bus
Terminal Bus Palermo
Aeroporto Ciampino Airport (CIA)
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Next departures for Palermo to Rome on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Tiburtina
CheapestFastest
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Bus
Terminal Bus Palermo
Rome Anagnina
No tags
Next departures for Palermo to Rome on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Rome Fiumicino Airport
Cheapest
Bus
Terminal Bus Palermo
Tiburtina
Fastest
Bus
Terminal Bus Palermo
Aeroporto Ciampino Airport (CIA)
No tags
Bus
Terminal Bus Palermo
Rome Tiburtina Bus Station
No tags
Last refresh of the prices: Today at 6:23 PM CET.
Compare 3 ways to go from Palermo to Rome
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Rome. The journey takes about 10 hours 50 minutes and with fares starting at just $63, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
According to 11 reviews, Autoservizi Salemi received a 4.5-star rating for this journey. Travelers were especially satisfied with the staff and the timeliness, but some complained about the ticket access. Autoservizi Salemi ticket prices on this trip start at $27
Based on 941 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the ticket access and the temperature but often complained with the timeliness. Itabus ticket prices on this trip start at $80
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Palermo to Rome by bus
How far is Palermo from Rome?
About 265 miles (428 km) separate Palermo and Rome.
What are the departure and arrival stations when taking the bus from Palermo to Rome?
Most of the buses traveling from Palermo to Rome leave from Terminal Bus Palermo and arrive at Rome Tiburtina Bus Station. These are the main departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Rome?
Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are Museo Nazionale Etrusco di Villa Giulia, Museo di Roma, Galleria Borghese, Parco degli Acquedotti and Colosseum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/11
$72
11/12
$72
Today
$46
11/14
$72
11/15
$52
11/16
$72
11/17
$60
11/18
$60
The cheapest trip from Palermo to Rome was searched and found on Nov 13, 2025 with a price of $46
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Rome, as early as possible.
You can expect to pay from $46 to $149 for a bus ticket from Palermo to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-11-15.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.