Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal Bus Palermo | Rome Tiburtina Bus Station | Cheapest | |||||
 | Terminal Bus Palermo | Tiburtina | Fastest | |||||
| Terminal Bus Palermo | Aeroporto Ciampino Airport (CIA) | No tags | |||||
| Terminal Bus Palermo | Rome Fiumicino Airport | No tags | |||||
| Terminal Bus Palermo | Rome Fiumicino Airport | No tags |
Last refresh of the prices: Today at 10:29 AM CET.
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Compare 3 ways to travel from Palermo to Rome
We recommend carpoolingAmong the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 10 hours 50 minutes and with fares starting at just US$63, it presents an excellent value for a comfortable ride.
Bus Palermo to Rome: Trip Overview
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Palermo to Rome Bus
With Busbud, comparing and booking tickets for a bus from Palermo to Rome is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Palermo to Rome.
Discover how much the bus trip from Palermo to Rome will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Palermo and Rome?
Frequently asked questions on the trip Palermo - Rome
How much does a bus ticket from Palermo to Rome cost?
The bus ticket price from Palermo to Rome starts at US$26. The best way to find cheap bus tickets from Palermo to Rome is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Palermo to Rome?
The average travel time between Palermo and Rome is around 18h 25m, although the fastest bus will take about 12h. This is the time it takes to travel the 428 km that separates the two cities.
How many daily bus connections are there between Palermo and Rome?
The number of buses from Palermo to Rome can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Palermo to Rome by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Palermo to Rome?
When taking the bus from Palermo to Rome, you can travel comfortably and safely with FlixBus, Autoservizi Salemi, Itabus.
What are the departure and arrival stations when taking the bus from Palermo to Rome?
Buses travelling between Palermo and Rome leave from Terminal Bus Palermo or Palermo Airport and arrive at Rome Tiburtina Bus Station, Rome Ciampino Airport, Rome Fiumicino Airport.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Rome was searched and found on 05 Nov 2025 with a price of US$59To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Rome as early as possible.
You can expect to pay from US$59 to US$256 for a bus ticket from Palermo to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at US$59, which is on 2025-11-05.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Palermo to Rome.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Palermo to Rome.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Palermo to Rome will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Palermo to Rome.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Palermo
Buses Leaving from Palermo
- Bus from Palermo to Frosinone
- Coach Palermo - Porto
- Bus Palermo - Modena
- Bus from Palermo to Maglie
- Coach Palermo - Catania
- Bus Palermo - Trapani
- Bus from Palermo to Barletta
- Coach Palermo - Petrosino
- Bus Palermo - Parma
- Bus from Palermo to Marina di Pietrapaola
- Coach Palermo - Milano
- Bus Palermo - Campobasso
- Bus from Palermo to Florence
- Coach Palermo - Cremona
- Bus Palermo - Porto Sant'Elpidio
Buses Going to Palermo
- Bus from Frosinone to Palermo
- Coach Bari - Palermo
- Bus Cosenza - Palermo
- Bus from Modena to Palermo
- Coach Outlet - Palermo
- Bus Catania - Palermo
- Bus from San Benedetto del Tronto to Palermo
- Coach Gallipoli - Palermo
- Bus Lecce - Palermo
- Bus from Alessandria to Palermo
- Coach Stazione di Mandatoriccio - Palermo
- Bus Pistoia - Palermo
- Bus from Perugia to Palermo
- Coach Giulianova - Palermo
- Bus Pordenone - Palermo
Popular Buses Connecting Rome
Buses Leaving from Rome
- Bus from Rome to Como
- Coach Rome - Fiumicino
- Bus Rome - Naples
- Bus from Rome to Tours
- Coach Rome - Outlet
- Bus Rome - Amalfi
- Bus from Rome to Monselice
- Coach Rome - San Severo
- Bus Rome - Oulx
- Bus from Rome to Caltanissetta
- Coach Rome - Verona
- Bus Rome - Spezzano Scalo
- Bus from Rome to Sparvasile
- Coach Rome - Misano Adriatico
- Bus Rome - Grottaminarda
Buses Going to Rome
- Bus from Milano to Rome
- Coach Venice - Rome
- Bus Civitavecchia - Rome
- Bus from Rimini to Rome
- Coach Barcelona - Rome
- Bus Nice - Rome
- Bus from Gallipoli to Rome
- Coach Terlizzi - Rome
- Bus Benevento - Rome
- Bus from Barletta to Rome
- Coach Pozzallo - Rome
- Bus Ostuni - Rome
- Bus from Bitonto to Rome
- Coach Marsico Nuovo - Rome
- Bus Amalfi - Rome