Bus Tickets from Panama City, US to Wytheville

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Previously seen trips

One passenger / one way

  • Departure time: February 1 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: February 3 at
    Destination city: Wytheville
    Destination location: Wytheville Bus Station
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: February 9 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: February 11 at
    Destination city: Wytheville
    Destination location: Wytheville Bus Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: March 25 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: March 27 at
    Destination city: Wytheville
    Destination location: Wytheville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: April 23 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: April 25 at
    Destination city: Wytheville
    Destination location: Wytheville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: May 10 at
    Destination city: Wytheville
    Destination location: Wytheville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Panama City, US to Wytheville: Trip Overview

Average ticket price$140
Average bus trip duration20h 20m
Number of daily buses2
Earliest bus departure7:40am
Distance546 miles (880 km)
Latest bus departure12:50pm

Panama City to Wytheville Bus

With Busbud, comparing and booking tickets for a bus from Panama City to Wytheville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Panama City to Wytheville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Panama City to Wytheville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Panama City, US - Wytheville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/06
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09/07
$187
Today
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09/09
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09/10
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09/11
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busbud logoThe cheapest trip from Panama City, US to Wytheville was searched and found on Sep 7, 2025 with a price of $187

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Wytheville, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Panama City to Wytheville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Wytheville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Panama City to Wytheville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Panama City to Wytheville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Panama City, US by bus?

Bus from Wytheville to Panama City, US

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