Bus Tickets from Orlando, FL to San Diego, CA

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TodayMay 14
from $412
TomorrowMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19
TueMay 20
WedMay 21

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 14 at
    Departure city: Orlando
    Departure location: The Florida Mall
    Arrival time: May 17 at
    Destination city: San Diego
    Destination location: Balboa Park
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 14 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 17 at
    Destination city: San Diego
    Destination location: Downtown SD (Seaport)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 17 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 17 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 17 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Orlando to San Diego.

Bus
Average Price$236 - $588Average Duration2d 16h
86kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$549 - $700Average Duration4d 2h
313kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Orlando to San Diego

Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 2 days, 16 hours 40 minutes and with fares starting at just $236, it presents an excellent value for a comfortable ride.

16bus per day
2d 16hAverage Duration
$236Cheapest ticket
86kgCO₂ emissions

Bus Orlando to San Diego: Trip Overview

Average ticket price$477
Average bus trip duration2d 16h
Number of daily buses16
Earliest bus departure5:15am
Distance2130 miles (3435 km)
Latest bus departure9:00pm

Orlando to San Diego Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to San Diego.

We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to San Diego.

Discover how much the bus trip from Orlando to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Orlando - San Diego

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/12
No data
05/13
$229
Today
$443
05/15
No data
05/16
No data
05/17
No data
05/18
No data
05/19
No data
busbud logoThe cheapest trip from Orlando to San Diego was searched and found on May 13, 2025 with a price of $229

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to San Diego, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Orlando to San Diego.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Orlando to San Diego will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Orlando to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Orlando to San Diego?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Orlando by bus?

Bus from Orlando to San Diego

You can also go to San Diego by train

Train from Orlando to San Diego

Why choose Busbud?

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