Bus Tickets from Lyon to Santander

Previously seen trips

Next departures for Lyon to Santander on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSA
Perrache
Calle Navas de Tolosa, 2No tags
FlixBus
Perrache
Santander (Estacion de Autobuses)No tags
FlixBus
Lyon
Santander (Estacion de Autobuses)No tags
FlixBus
Aéroport LYS
Santander (Estacion de Autobuses)No tags
FlixBus
Lyon
Santander (Estacion de Autobuses)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Lyon to Santander.

Bus
Average Price$60 - $186Average Duration20h 5m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$74 - $74Average Duration11h
31kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Lyon to Santander

Among the sustainable travel choices, the carpool stands out as the good way to reach Santander. The journey takes about 11 hours and with fares starting at just $74, it presents an excellent value for a comfortable ride.

1carpool per day
11hAverage Duration
$74Cheapest ticket
31kgCO₂ emissions

Bus Lyon to Santander: Trip Overview

Average ticket price$145
Average bus trip duration20h 5m
Number of daily buses1
Earliest bus departure5:10am
Distance452 miles (729 km)
Latest bus departure11:59pm

Lyon to Santander Bus

Busbud helps you find a bus from Lyon to Santander. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Lyon to Santander from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Lyon - Santander

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/01
$45
10/02
$45
Today
$45
10/04
$45
10/05
$49
10/06
$54
10/07
$55
10/08
$79
busbud logoThe cheapest trip from Lyon to Santander was searched and found on Oct 1, 2025 with a price of $45

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Santander, as early as possible.

You can expect to pay from $45 to $138 for a bus ticket from Lyon to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $45 which is on 2025-10-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lyon and Santander!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Santander, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Lyon to Santander.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Lyon by bus?

Bus from Santander to Lyon

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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