Bus from Madrid to Santander: Tickets & Schedules

Next bus departures

Next departures for Madrid to Santander on March 20
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSABus
Avenida de América Metro
Santander (Estacion de Autobuses)Cheapest
ALSA SupraBus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)Fastest
ALSA SupraBus
Avenida de América Metro
Santander (Estacion de Autobuses)No tags
ALSA SupraBus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)No tags
ALSABus
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
Santander (Estacion de Autobuses)No tags

Last refresh of the prices: Today at 3:52 PM CET.

Compare 2 ways to go from Madrid to Santander

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Santander. The journey takes about 4 hours 21 minutes and with fares starting at just $33, it presents an excellent value for a comfortable ride.

2train per day
4h 21mAverage Duration
206 milesDistance
8kgCO₂ emissions
Average Price$39 - $125Average Duration5h 30m
8kg CO₂e
Average Price$33 - $115Average Duration4h 21m
8kg CO₂e

Frequently asked questions about traveling from Madrid to Santander by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Madrid to Santander?

    The cheapest bus tickets from Madrid to Santander start from $39. The average price for this route is around $54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Madrid to Santander?

    The average bus trip duration from Madrid to Santander is 5h 30m, covering a distance of 205 miles (331 km). The quickest bus can get you there in 4h 45m and is operated by ALSA.

  3. Which bus companies service the Madrid to Santander route?

    Several major bus companies operate on this route with 14 buses available per day, including services from ALSA, FlixBus.

  4. What is the earliest and latest departure time for the bus from Madrid to Santander?

    The earliest bus departs from Madrid to Santander at 12:30am. And the latest bus departs at 11:30pm.

  5. What are the CO₂ emissions for the bus trip from Madrid to Santander?

    A bus trip from Madrid to Santander generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Madrid to Santander?

    According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61438 reviews.

  7. Which bus company has the best Wi-Fi from Madrid to Santander?

    Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.

  8. Which bus company has the most timely service from Madrid to Santander?

    According to Busbud traveler reviews, the most timely bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

  9. Which bus company has the cleanest buses from Madrid to Santander?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/17
$48
03/18
$48
Today
$47
03/20
$46
03/21
$43
03/22
$46
03/23
$43
03/24
$42
busbud logoThe cheapest trip from Madrid to Santander was searched and found on Mar 24, 2026 with a price of $42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Santander, as early as possible.

You can expect to pay from $42 to $67 for a bus ticket from Madrid to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2026-03-24.

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