Bus from Santander to Madrid: Tickets & Schedules

Next bus departures

Next departures for Santander to Madrid on March 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSA SupraBus
Santander (Estacion de Autobuses)
Avenida de América MetroCheapest
ALSA SupraBus
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4Fastest
ALSA SupraBus
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
ALSA SupraBus
Santander (Estacion de Autobuses)
Avenida de América MetroNo tags
ALSABus
Santander (Estacion de Autobuses)
Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags

Last refresh of the prices: Today at 1:45 AM CET.

Compare 2 ways to go from Santander to Madrid

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Madrid. The journey takes about 4 hours 24 minutes and with fares starting at just $34, it presents an excellent value for a comfortable ride.

2train per day
4h 24mAverage Duration
206 milesDistance
8kgCO₂ emissions
Bus
Average Price$41 - $148Average Duration5h 40m
8kg CO₂e
Train
Average Price$34 - $89Average Duration4h 24m
8kg CO₂e

Frequently asked questions about traveling from Santander to Madrid by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Santander to Madrid?

    The cheapest bus tickets from Santander to Madrid start from $41. The average price for this route is around $55. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Santander to Madrid?

    The average bus trip duration from Santander to Madrid is 5h 40m, covering a distance of 209 miles (337 km). The quickest bus can get you there in 4h 30m and is operated by ALSA.

  3. Which bus companies service the Santander to Madrid route?

    Several major bus companies operate on this route with 13 buses available per day, including services from ALSA, FlixBus.

  4. What is the earliest and latest departure time for the bus from Santander to Madrid?

    The earliest bus departs from Santander to Madrid at 12:45am. And the latest bus departs at 6:50pm.

  5. What are the CO₂ emissions for the bus trip from Santander to Madrid?

    A bus trip from Santander to Madrid generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Santander to Madrid?

    According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61438 reviews.

  7. Which bus company has the best Wi-Fi from Santander to Madrid?

    Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.

  8. Which bus company has the most timely service from Santander to Madrid?

    According to Busbud traveler reviews, the most timely bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

  9. Which bus company has the cleanest buses from Santander to Madrid?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/15
$42
03/16
$46
Today
$43
03/18
$41
03/19
$41
03/20
$42
03/21
$41
03/22
$46
busbud logoThe cheapest trip from Santander to Madrid was searched and found on Mar 19, 2026 with a price of $41

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Madrid, as early as possible.

You can expect to pay from $41 to $67 for a bus ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $41 which is on 2026-03-19.

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