Bus Tickets from Houston, US to Des Moines

Previously seen trips

Next departures for Houston to Des Moines on October 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Houston Bus Station
Des Moines (Subway)No tags
Greyhound + Valley Transit
Hillcroft Ave & Southwest Freeway
Des Moines (Subway)No tags
Greyhound
Houston Bus Station
Des Moines (Subway)No tags
Greyhound + FlixBus
Downtown Gray & Smith
Des Moines (Subway)No tags
Greyhound + FlixBus
Houston Uptown/Upper Kirby
Des Moines (Subway)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Houston, US to Des Moines: Trip Overview

Average ticket price$234
Average bus trip duration1d 19h
Number of daily buses9
Earliest bus departure2:00am
Distance825 miles (1330 km)
Latest bus departure11:20pm

Houston to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Houston to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Houston to Des Moines from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Houston to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Houston, US - Des Moines

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/29
$215
09/30
No data
Today
No data
10/02
$215
10/03
No data
10/04
$215
10/05
$215
10/06
No data
busbud logoThe cheapest trip from Houston, US to Des Moines was searched and found on Sep 29, 2025 with a price of $215

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Des Moines, as early as possible.

You can expect to pay from $215 to $226 for a bus ticket from Houston, US to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $215 which is on 2025-10-02.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Houston to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Houston to Des Moines, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Houston to Des Moines that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Houston to Des Moines.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Houston, US by bus?

Bus from Des Moines to Houston, US

Why choose Busbud?

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