Next departures for Houston to San Diego on December 4
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Baytown, 6800 Thompson Rd
Greyhound Bus Stop
Cheapest
Bus
Houston Bus Station
Greyhound Bus Stop
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Houston Bus Station
Greyhound Bus Stop
No tags
FlixBus + Valley Transit + Greyhound Lines, Inc.
Bus
Downtown Gray & Smith
San Diego (Old Town-FlixBus)
No tags
Next departures for Houston to San Diego on December 5
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Baytown, 6800 Thompson Rd
Greyhound Bus Stop
Cheapest
Bus
Houston Bus Station
Greyhound Bus Stop
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Houston Bus Station
Greyhound Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
Hillcroft Ave & Southwest Freeway
San Diego (Old Town-FlixBus)
No tags
Next departures for Houston to San Diego on December 6
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
Cheapest
Bus
Houston Bus Station
Greyhound Bus Stop
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Houston Bus Station
Greyhound Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
Hillcroft Ave & Southwest Freeway
San Diego (Old Town-FlixBus)
No tags
Next departures for Houston to San Diego on December 7
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
Downtown SD (Seaport)
Cheapest
Bus
Houston Bus Station
Greyhound Bus Stop
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Houston Bus Station
Greyhound Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
Hillcroft Ave & Southwest Freeway
Greyhound Bus Stop
No tags
Next departures for Houston to San Diego on December 8
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
Cheapest
Bus
Houston Bus Station
Greyhound Bus Stop
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Houston Bus Station
Greyhound Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc.
Bus
Hillcroft Ave & Southwest Freeway
Greyhound Bus Stop
No tags
Next departures for Houston to San Diego on December 10
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
UCSD Health La Jolla Station
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Houston Bus Station
San Diego (Old Town-FlixBus)
No tags
Bus
Houston Bus Station
Greyhound Bus Stop
No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus
Bus
Hillcroft Ave & Southwest Freeway
San Diego (Old Town-FlixBus)
No tags
Last refresh of the prices: Last Saturday at 10:34 AM CST.
Compare 2 ways to go from Houston to San Diego
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 1 day, 16 hours 55 minutes and with fares starting at just $202, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Houston San Diego recent customer reviews
Two connections were very late but the drivers made up the time. One driver was very nasty and rude but other than that it was okay
4 out of 5 stars
Edward W.
I appreciated all the help from Iris at the Houston Station She was amazing, changed all my trip to the better! Thanks!!
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 34 reviews, the company was rated 3 stars on Busbud. Travelers were especially satisfied with the departure location and the staff but often complained with the wifi. Valley Transit ticket prices on this trip start at $118
Frequently asked questions about traveling from Houston, US to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Houston to San Diego?
The cheapest bus tickets from Houston to San Diego start from $135. The average price for this route is around $238. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to San Diego?
The average bus trip duration from Houston to San Diego is 1d 22h, covering a distance of 1299 miles (2094 km). The quickest bus can get you there in 1d 11h and is operated by Greyhound.
Which bus companies service the Houston to San Diego route?
Several major bus companies operate on this route with 36 buses available per day, including services from Greyhound, FlixBus, Valley Transit.
What is the earliest and latest departure time for the bus from Houston to San Diego?
The earliest bus departs from Houston to San Diego at 2:00am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to San Diego?
A bus trip from Houston to San Diego generates an estimated 52 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Houston to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87412 reviews.
Which bus company has the best Wi-Fi from Houston to San Diego?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Houston to San Diego?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Houston to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/02
$405
12/03
$332
Today
$199
12/05
$217
12/06
$191
12/07
$172
12/08
$201
12/09
No data
The cheapest trip from Houston, US to San Diego, CA, US was searched and found on Dec 7, 2025 with a price of $172
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to San Diego, CA, US, as early as possible.
You can expect to pay from $172 to $444 for a bus ticket from Houston, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $172 which is on 2025-12-07.
What's the cheapest way to go from Houston, US to San Diego, CA, US?
The bus is the cheapest travel choice for this destination