Bus Tickets from Greenville, SC to Boston, MA, US

Next departures

Next departures for Greenville to Boston on October 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Boston (South Station)Cheapest
FlixBus
1116 Woodruff Rd
BrooklineFastest
Greyhound Lines, Inc.
1116 Woodruff Rd
Boston (South Station)No tags
FlixBus
1116 Woodruff Rd
Boston (South Station)No tags
FlixBus + Greyhound Lines, Inc.
1116 Woodruff Rd
Boston (South Station)No tags

Last refresh of the prices: Today at 5:29 PM EDT.

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Compare 2 ways to go from Greenville to Boston.

Bus
Average Price$72 - $228Average Duration22h 55m
32kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$176 - $500Average Duration21h 47m
116kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Greenville to Boston

Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 22 hours 55 minutes and with fares starting at just $72, it presents an excellent value for a comfortable ride.

9bus per day
22h 55mAverage Duration
$72Cheapest ticket
32kgCO₂ emissions

Bus Greenville, SC to Boston, MA, US: Trip Overview

Average ticket price$109
Average bus trip duration22h 55m
Number of daily buses9
Earliest bus departure7:25am
Distance794 miles (1280 km)
Latest bus departure10:00pm

Greenville to Boston Bus

With Busbud, comparing and booking tickets for a bus from Greenville to Boston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Greenville to Boston will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Boston from Greenville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Greenville, SC - Boston, MA, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/30
$95
10/01
$65
Today
$83
10/03
$96
10/04
$85
10/05
$101
10/06
$71
10/07
No data
busbud logoThe cheapest trip from Greenville, SC to Boston, MA, US was searched and found on Oct 1, 2025 with a price of $65

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Boston, MA, US, as early as possible.

You can expect to pay from $65 to $160 for a bus ticket from Greenville, SC to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $71 which is on 2025-10-06.

Usually Greyhound, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Greenville to Boston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Greenville to Boston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Greenville to Boston.

Tune out to the fine sounds of your best music playlist on your bus trip from Greenville to Boston while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Greenville, SC to Boston, MA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville, SC by bus?

Bus from Boston, MA, US to Greenville, SC

You can also go to Boston, MA, US by train

Train from Greenville, SC to Boston, MA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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