Compare 2 ways to go from Boston to Greenville.
Busbud recommends taking the train from Boston to GreenvilleAmong the sustainable travel choices, the train stands out as the good way to reach Greenville. The journey takes about 20 hours 56 minutes and with fares starting at just $197, it presents an excellent value for a comfortable ride.
Bus Boston, MA, US to Greenville, SC: Trip Overview
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Boston to Greenville Bus
Busbud helps you find a bus from Boston to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Boston to Greenville will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Greenville from Boston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Boston and Greenville?
Frequently asked questions for your trip Boston, MA, US - Greenville, SC
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on Aug 11, 2025 with a price of $89To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Greenville, SC, as early as possible.
You can expect to pay from $89 to $249 for a bus ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $89 which is on 2025-08-11.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Boston and Greenville!
Much more than a mere vehicle taking you from Boston to Greenville, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Boston to Greenville.
Tune out to the fine sounds of your best music playlist on your bus trip from Boston to Greenville while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Boston, MA, US to Greenville, SC?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular Buses Connecting Boston
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Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Spartanburg
- Bus Greenville - Charleston
- Greenville - Charleston
- Bus from Greenville to Greensboro
- Bus Greenville - Chicago
- Greenville - Miami
- Bus from Greenville to Atlanta
- Bus Greenville - Charlotte
- Greenville - New York City
- Bus from Greenville to Knoxville
- Bus Greenville - Tarboro
- Greenville - Anderson
- Bus from Greenville to Macon
- Bus Greenville - Orlando
- Greenville - Dallas
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Bus Burlington - Greenville
- Nashville - Greenville
- Bus from Knoxville to Greenville
- Bus Savannah - Greenville
- Charlotte - Greenville
- Bus from Charleston to Greenville
- Bus Anderson - Greenville
- Asheville - Greenville
- Bus from New York City to Greenville
- Bus LaGrange - Greenville
- Miami - Greenville
- Bus from Fayetteville to Greenville
- Bus Washington - Greenville