- Buffalo to Chicago buses
Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Niagara Frontier Transportation Authority | Chicago 95Th & Dan Ryan | Cheapest | ||||
![]() | Bus | Niagara Frontier Transportation Authority | Downtown Greyhound Station | Fastest | ||||
![]() | Bus | Niagara Frontier Transportation Authority | 537-517 W. Jackson Blvd | No tags |
Last refresh of the prices: Today at 1:59 PM EST.
Compare 2 ways to go from Buffalo to Chicago
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 10 hours 33 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.
1train per day
10h 33mAverage Duration
460 milesDistance
67kgCO₂ emissions
Compare bus companies
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Where are the popular stops in Buffalo and Chicago?
Stops in Buffalo
Stops in Chicago
Frequently asked questions about traveling from Buffalo, NY to Chicago by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/12
$97
11/13
$124
Today
$106
11/15
$100
11/16
$134
11/17
$70
11/18
$69
11/19
$70
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Chicago, as early as possible.
You can expect to pay from $69 to $181 for a bus ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-11-18.
What's the cheapest way to go from Buffalo, NY to Chicago?
Top traveled bus routes
People from around the world trust Busbud
Popular Buses Connecting Buffalo
Buses Leaving from Buffalo
- Bus from Buffalo to New York City
- Bus Buffalo - Buffalo
- Buffalo - Boston
- Bus from Buffalo to Miami
- Bus Buffalo - Kansas City
- Buffalo - Toronto
- Bus from Buffalo to Cleveland
- Bus Buffalo - Albany
- Buffalo - Rochester
- Bus from Buffalo to Detroit
- Bus Buffalo - Ithaca
- Buffalo - Newark
- Bus from Buffalo to Philadelphia
- Bus Buffalo - Chicago
- Buffalo - Erie
Buses Going to Buffalo
- Bus from New York City to Buffalo
- Bus Springfield - Buffalo
- Springfield - Buffalo
- Bus from Springfield to Buffalo
- Bus Springfield - Buffalo
- Jackson - Buffalo
- Bus from Niagara Falls to Buffalo
- Bus Elmira - Buffalo
- Chicago - Buffalo
- Bus from Rochester to Buffalo
- Bus Albany - Buffalo
- Boston - Buffalo
- Bus from Newark to Buffalo
- Bus Cleveland - Buffalo
- Corning - Buffalo
Popular Buses Connecting Chicago
Buses Leaving from Chicago
- Bus from Chicago to Columbia
- Bus Chicago - Washington
- Chicago - Washington
- Bus from Chicago to Toronto
- Bus Chicago - Mexico City
- Chicago - Orlando
- Bus from Chicago to Madison
- Bus Chicago - Indianapolis
- Chicago - Milwaukee
- Bus from Chicago to Green Bay
- Bus Chicago - Rockford
- Chicago - New York City
- Bus from Chicago to Minneapolis
- Bus Chicago - Champaign
- Chicago - Los Angeles
Buses Going to Chicago
- Bus from Boston to Chicago
- Bus Indianapolis - Chicago
- Atlanta - Chicago
- Bus from Toronto to Chicago
- Bus Bridgeport - Chicago
- Hamilton - Chicago
- Bus from Madison to Chicago
- Bus New York City - Chicago
- Green Bay - Chicago
- Bus from Lafayette to Chicago
- Bus Milwaukee - Chicago
- Minneapolis - Chicago
- Bus from Savannah to Chicago
- Bus Detroit - Chicago
- Rockford - Chicago
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Miami - Tampa
- Austin - Houston
- Bus from Houston to San Antonio
- Bus Houston - Austin
- Seattle - Leavenworth
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Providence - New York City







