What is the travel distance from Buffalo to Chicago?

About 453 miles (731 km) separate Buffalo and Chicago.

What are the departure and arrival stations when taking the bus from Buffalo to Chicago?

The majority of buses traveling from Buffalo to Chicago start their journey at Buffalo Airport and wind up at Downtown Greyhound Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Chicago?

Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Cloud Gate, Architectural River Cruise, Museum of Science and Industry, Brookfield Zoo and Chicago Shakespeare Theater on Navy Pier.

Bus Buffalo to Chicago from $58 | Refundable Tickets

Next bus departures

Next departures for Buffalo to Chicago on November 16
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:55am	Niagara Frontier Transportation Authority	15h 30m	10:25pm	Chicago 95Th & Dan Ryan	Cheapest
Bus	7:55am	Niagara Frontier Transportation Authority	13h 10m	8:05pm	Downtown Greyhound Station	Fastest
Bus	7:55am	Niagara Frontier Transportation Authority	1d	7:50am	537-517 W. Jackson Blvd	No tags

Last refresh of the prices: Today at 1:59 PM EST.

Compare 2 ways to go from Buffalo to Chicago

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 10 hours 33 minutes and with fares starting at just $56, it presents an excellent value for a comfortable ride.

1train per day

10h 33mAverage Duration

460 milesDistance

67kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$56 - $135	Average Duration15h 30m	CO₂ emissions 18kg CO₂e
Train	Average Price$56 - $197	Average Duration10h 33m	CO₂ emissions 67kg CO₂e

Compare bus companies

Greyhound

3.5/587,372 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Buffalo Chicago recent customer reviews

Very unhappy with our travel from Buffalo to Chicago. The bus from buffalo to cleavelent was an hour late which was not the the biggest drama however the problem was that the greyhound bus station in both buffalo and cleavelend was very miserable, cold, dirty and smelly and most of all looking very unsafe. The whole experience really made us not want to travel with a bus anymore in our life.

Pamela D.

September 18, 2018

Before was good but yesterday i was shocked because i could not move back of my seat .most of the seat greyhound should fixed

Mostafa S.

March 29, 2018

I am dissatisfied with the services of Greyhound. Unsystematic and slow work.

Preeti N.

June 16, 2019

FlixBus

3.5/511,316 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Buffalo and Chicago?

Stops in Buffalo

A - Buffalo Airport

B - Transportation Center

C - Exchange Street Station

Stops in Chicago

A - Downtown Greyhound Station

B - Chicago O'Hare International Airport

C - Polk St & Canal St

D - Tornado Bus S Kedzie Ave

E - Cumberland CTA

F - Turimex California Ave

Frequently asked questions about traveling from Buffalo, NY to Chicago by bus

What is the travel distance from Buffalo to Chicago?
What are the departure and arrival stations when taking the bus from Buffalo to Chicago?
What are the best sights and things to do in Chicago?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/12

$97

11/13

$124

Today

$106

11/15

$100

11/16

$134

11/17

$70

11/18

$69

11/19

$70

The cheapest trip from Buffalo, NY to Chicago was searched and found on Nov 18, 2025 with a price of $69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Chicago, as early as possible.

You can expect to pay from $69 to $181 for a bus ticket from Buffalo, NY to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-11-18.