Find coaches from Pittsburgh to Greenville, SC

Find affordable coach tickets from Pittsburgh to Greenville, SC with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Mon11 Aug
Tue12 Aug
from US$92
Wed13 Aug
Thu14 Aug
from US$97
Fri15 Aug
from US$94
Sat16 Aug
Sun17 Aug
Mon18 Aug

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 12 August at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 12 August at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 12 August at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: 13 August at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Pittsburgh to Greenville

Bus
Average priceUS$92 - US$215Average duration18h 10m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$199 - US$412Average duration23h 59m
60kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Pittsburgh to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 10 minutes and with fares starting at just US$92, it presents an excellent value for a comfortable ride.

3bus per day
18h 10mAverage duration
US$92Cheapest ticket
16kgCO₂ emissions

Bus Pittsburgh to Greenville, SC: Trip Overview

Average ticket priceUS$115
Average bus trip duration18h 10m
Number of daily buses3
Earliest bus departure01:35
Distance408 miles
Latest bus departure23:10

Pittsburgh to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Pittsburgh to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Pittsburgh to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Pittsburgh, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Pittsburgh - Greenville, SC

  1. How far is Greenville from Pittsburgh by coach?

    The journey from Pittsburgh to Greenville by coach covers an approximate distance of 408 miles (657 km).

  2. Is there a way to reach Greenville from Pittsburgh without flying?

    To travel from Pittsburgh to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/08
No data
08/08
US$113
Today
No data
10/08
US$107
11/08
No data
12/08
US$93
13/08
No data
14/08
US$89
busbud logoThe cheapest trip from Pittsburgh to Greenville, SC was searched and found on 14 Aug 2025 with a price of US$89

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Greenville, SC as early as possible.

You can expect to pay from US$89 to US$138 for a bus ticket from Pittsburgh to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$89, which is on 2025-08-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Pittsburgh to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Pittsburgh to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Pittsburgh to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from Pittsburgh to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Pittsburgh to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pittsburgh by bus?

Bus from Pittsburgh to Greenville, SC

You can also go to Greenville, SC by train

Train from Pittsburgh to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Pittsburgh

Buses Leaving from Pittsburgh

Buses Going to Pittsburgh

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville