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- This trip is recommended because it is the: Cheapest + Fastest
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Compare 2 ways to travel from Greenville to Pittsburgh
Among the sustainable travel choices, the bus stands out as a good way to reach Pittsburgh. The journey takes about 16 hours 20 minutes and with fares starting at just US$82, it presents an excellent value for a comfortable ride.
Bus Greenville, SC to Pittsburgh: Trip Overview
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Greenville to Pittsburgh Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Pittsburgh.
We make sure you can find a bus service from Greenville to Pittsburgh from the most reliable bus companies operating this trip.
Discover how much the bus trip from Greenville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Greenville and Pittsburgh?
Frequently asked questions on the trip Greenville, SC - Pittsburgh
What's the distance between Greenville and Pittsburgh by coach?
The journey from Greenville to Pittsburgh by coach covers an approximate distance of 408 miles (657 km).
What is the best way to go from Greenville to Pittsburgh without flying?
You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Pittsburgh as early as possible.
You can expect to pay from US$119 to US$125 for a bus ticket from Greenville, SC to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at US$119, which is on 2025-08-12.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Pittsburgh but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Pittsburgh, get comfy and count the stars.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Pittsburgh will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Pittsburgh.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Greenville, SC to Pittsburgh?
Top travelled bus routes
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Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Coach Greenville - Spartanburg
- Bus Greenville - Charleston
- Greenville - Greensboro
- Bus from Greenville to Chicago
- Coach Greenville - Miami
- Bus Greenville - Columbus
- Greenville - Oklahoma City
- Bus from Greenville to New York City
- Coach Greenville - San Antonio
- Bus Greenville - Atlanta
- Greenville - Anderson
- Bus from Greenville to Charlotte
- Coach Greenville - Lima
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Coach Burlington - Greenville
- Bus Nashville - Greenville
- Knoxville - Greenville
- Bus from Savannah to Greenville
- Coach Charlotte - Greenville
- Bus Myrtle Beach - Greenville
- Lima - Greenville
- Bus from Memphis to Greenville
- Coach Spartanburg - Greenville
- Bus Dublin - Greenville
- Miami - Greenville
- Bus from Durham to Greenville
- Coach Pittsburgh - Greenville
Popular Buses Connecting Pittsburgh
Buses Leaving from Pittsburgh
Buses Going to Pittsburgh
- Bus from Temple to Pittsburgh
- Coach Greensburg - Pittsburgh
- Bus Hamilton - Pittsburgh
- Boston - Pittsburgh
- Bus from Bakersfield to Pittsburgh
- Coach New York City - Pittsburgh
- Bus Philadelphia - Pittsburgh
- Washington - Pittsburgh
- Bus from Silver Spring to Pittsburgh
- Coach Baltimore - Pittsburgh
- Bus Columbus - Pittsburgh
- Gainesville - Pittsburgh
- Bus from Tampa to Pittsburgh
- Coach Iowa City - Pittsburgh
Popular routes in this country
- Bus from New York City to Burlington
- Coach Austin - Houston
- Bus Niagara Falls - New York City
- Dallas - Austin
- Bus from Houston to Austin
- Coach Austin - Dallas
- Bus Atlanta - Savannah
- Philadelphia - New York City
- Bus from Tallahassee to Panama City
- Coach New York City - Los Angeles
- Bus Baton Rouge - New Orleans
Popular airport transfers
- Travel in United States
- Bus to Greenville, SC
- Bus to Pittsburgh
- Greenville, SC to Pittsburgh Buses